Post-coital antifertility activity of Acalypha indica L |
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Authors: | Hiremath S P Rudresh K Badami S Patil S B Patil S R |
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Institution: | Department of Chemistry, Gulbarga University, India. |
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Abstract: | Four successive solvent extracts of the whole plant Acalypha indica L. (Euphorbiaceae) were tested for post-coital antifertility activity in female albino rats. Of these, the petroleum ether and ethanol extracts were found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdrawal of the treatment of the extracts. Both the extracts at 600 mg/kg body weight showed estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity. |
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