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扶正抗癌汤联合FOLFOX4方案治疗晚期胃癌临床观察
引用本文:乔炳礼.扶正抗癌汤联合FOLFOX4方案治疗晚期胃癌临床观察[J].山西中医,2012,28(2):33-34.
作者姓名:乔炳礼
作者单位:陕西中医学院 咸阳712000
摘    要:目的:观察扶正抗癌汤联合FOLFOX4方案治疗晚期胃癌的疗效。方法:60例晚期胃癌患者随机分为两组各30例。对照组单用FOLFOX4方案化疗,治疗组用FOLFOX4联合扶正抗癌汤方案治疗。结果:治疗组近期疗效总缓解率为56.7%(95%CI=39.0%~74.4%),对照组为40.0%(95%CI=22.5%~57.5%),两组比较(u=1.371 2,P>0.05),差异无显著性意义;两组临床症状积分评价,治疗组优于对照组(t’=-26.364 0,P<0.01);毒副反应分度评价,治疗组较对照组为轻(u=2.863 1,P=0.006 4);治疗组KPS评分有效率为71.07%,对照组为34.31%,有显著显著差异(u=2.849 1,P=0.0066)。结论:FOLFOX4方案联合扶正抗癌汤治疗晚期胃癌能明显改善患者的临床症状,减低FOLFOX4化疗的副反应,增强疗效和提高患者的生存质量。

关 键 词:胃癌  扶正抗癌汤  FOLFOX4方案  中西医结合疗法

Clinical Observation of Decoction of Kang-ai Fu-zheng Combined with FOLFOX4 Scheme on Late Gastric Cancer
QIAO Bing-li.Clinical Observation of Decoction of Kang-ai Fu-zheng Combined with FOLFOX4 Scheme on Late Gastric Cancer[J].Shanxi Journal of Traditional Chinese Medicine,2012,28(2):33-34.
Authors:QIAO Bing-li
Institution:QIAO Bing-li( Shanxi TCM College ,Xianyang,712000, China)
Abstract:Objective:To observe the curative effect of Decoction of Kang-ai Fu-zheng combined with FOL- FOX4 scheme on late gastric cancer. Methods :60 cases with late gastric cancer were divided into two groups randomly. 30 cases in control group were treated with FOLFOX4 scheme, and the other 30 ones in treatment group were treated with FOLFOX4 scheme combined with Decoction of Kang-ai Fu-zheng. Results:In treatment group the total effective rate in the near future was 56. 7% (95% CI = 39. 0% - 74. 4% ), and in control group 40. 0% (95%CI =22. 5% -57.5% ). There was not significant difference between the two groups (u =1. 371 2,P 〉 0. 05 ). But on clinical symptoms score treatment group was better than control group( t' = -26. 364 0 ,P 〈 0. 01 ). And on toxic and side effects treatment group was lighter than control group ( u = 2. 863 1, P = 0. 006 4 ). The effective power of KPS score was 71.07% in treatment group,and 34. 31% in control group. There was significant difference between the two groups ( u = 2. 849 1, P = 0. 006 6 ). Conclusion : FOLFOX4 scheme combined with Decoction of Kang-ai Fu-zheng can improve the clinical manifestation in late gastric cancer, reduce the side effect of FOLFOX4 scheme, enhance the curative effect, and improve the patients' quality of life.
Keywords:Decoction of Kang-ai Fu-zheng  FOLFOX4 scheme  gastric cancer  therapy of integrated traditional Chinese and western medicine
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