| 消岩汤不同时段联合化疗对Lewis肺癌小鼠免疫功能的影响 |
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| 引用本文： | 贾英杰,李小江,杨佩颖,孙一予,张蕴超,黄敏娜,包芳芳.消岩汤不同时段联合化疗对Lewis肺癌小鼠免疫功能的影响[J].天津中医药,2010,27(4):312-314. |
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| 作者姓名： | 贾英杰 李小江 杨佩颖 孙一予 张蕴超 黄敏娜 包芳芳 |
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| 作者单位： | 1. 天津中医药大学第一附属医院肿瘤科,天津,300193
2. 天津中医药大学,天津,300193 |
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| 基金项目： | 天津市科技支撑计划重点项目 |
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| 摘 要： | 目的]观察消岩汤对不同时段联合化疗对Lewis肺癌小鼠免疫功能的影响。方法]60只C57BL/6小鼠随机分为空白对照组、荷瘤空白组、单纯顺铂组、提前7d运用消岩汤加顺铂组、化疗前3d运用消岩汤加顺铂组和消岩汤同时加顺铂组。消岩汤灌胃第12天后,处死小鼠,观察小鼠生长活动情况、体质量、抑瘤率、脾脏指数、胸腺指数、血清干扰素(IFN-γ)、白介素-2(IL-2)含量的变化。结果]消岩汤提前介入化疗对Lewis肺癌小鼠有较好的抑瘤作用,生长活动状况也较好。化疗前运用消岩汤介入治疗Lewis肺癌小鼠胸腺指数、脾脏指数及IL-2、IFN-γ细胞因子分泌水平显著高于单纯化疗组。结论]消岩汤能保护实验动物的细胞免疫器官,提高小鼠的免疫功能。
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| 关 键 词： | 消岩汤 化疗 免疫功能 |
| 收稿时间： | 2010/2/11 0:00:00 |
The effects of Xiao Yan Tang different times are combined with chemotherapy on immune function of mice Lewis lung cancer |
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| JIA Ying-jie,LI Xiao-jiang,YANG Pei-ying.The effects of Xiao Yan Tang different times are combined with chemotherapy on immune function of mice Lewis lung cancer[J].Tianjin Journal of Traditional Chin Medicine,2010,27(4):312-314. |
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| Authors: | JIA Ying-jie LI Xiao-jiang YANG Pei-ying |
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| Institution: | The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China;The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China;The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China;The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China;The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China;The First Affiliated Hosptal of Tianjin University of Traditional Chinese Medcine Oncology, Tianjin 300193, China |
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| Abstract: | |
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| Keywords: | XiaoYanTang chemotherapy immune function |
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