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黄芪多糖对恶性肿瘤化疗后骨髓抑制的影响
引用本文:赵美蓉,周洁.黄芪多糖对恶性肿瘤化疗后骨髓抑制的影响[J].天津中医药,2007,24(2):114-115.
作者姓名:赵美蓉  周洁
作者单位:1. 天津中医药大学,天津,300193
2. 天津中医药大学第二附属医院,天津,300150
基金项目:天津市卫生局中医、中西医结合科研专项资助项目
摘    要:目的]探讨注射用黄芪多糖对恶性肿瘤化疗所致骨髓抑制的作用。方法]将48例患者随机分成治疗组26例,对照组22例。治疗组在化疗前给予注射用黄芪多糖250mg,1次/d,连续应用7d,对照组仅给予常规化疗。比较治疗开始后第4、7、10、14天白细胞、中性粒细胞及血小板计数。结果]治疗组对化疗所致的血象下降较对照组有明显提升。两组比较白细胞、中性粒细胞数在第10、14天时有显著性差异(P<0.05),血小板计数在第14天时有显著性差异(P<0.05)。结论]注射用黄芪多糖可显著减轻恶性肿瘤化疗后的骨髓抑制,改善患者生活质量。

关 键 词:黄芪多糖  恶性肿瘤  化疗  毒副作用  骨髓抑制
文章编号:1672-1519(2007)02-0114-02
收稿时间:2006/12/19 0:00:00
修稿时间:2006-12-19

Effect of astragalus polysaccharide on suppression of bone marrow after chemotherapy in patients with malignant tumor
ZHAO Mei-rong and ZHOU Jie.Effect of astragalus polysaccharide on suppression of bone marrow after chemotherapy in patients with malignant tumor[J].Tianjin Journal of Traditional Chin Medicine,2007,24(2):114-115.
Authors:ZHAO Mei-rong and ZHOU Jie
Institution:1.Tianjin University of TCM, Tianjin 300193, China; 2.The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China
Abstract:Objective] To explore the effect of astragalus polysaccharide on the suppression of bone marrow after chemotherapy in patients with malignant tumor. Methods] Eighty patients were randomly divided into treatment group and control group. The patients in treatment group (26 cases) were infused with astragalus polysaccharide intravenously, 250 mg daily from days 1 to 7 before chemotherapy, while the control group was treated with routine chemotherapy only. Then, the laboratory tests were performed after treatment and compared the change of white blood cell count, neutrophil count and platelet count at the 4, 7, 10 and 14 day. Results] The curative effect in treatment group was superior to that in control group. There was notable difference between two groups at the 10, 14 day(white blood cell count and neutrophil count) and at the 14 day (platelet count). Conclusions] Astragalus polysaccharide can significantly ameliorate the suppression of bone marrow after chemotherapy and improve the life quality of patients.
Keywords:astragalus polysaccharide  malignant tumor  chemotherapy side effect  suppression of bone marrow
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