通栓活络汤联合西药治疗痰瘀阻络型缺血性中风随机平行对照研究

目的]观察通栓活络汤治疗痰瘀阻络型缺血性中风疗效。方法]使用随机平行对照方法,将80例住院患者按就诊顺序编号简单随机分为两组。对照组40例奥扎格雷钠,80mg/次,1次/d,连续14d;阿司匹林肠溶片,100mg/次,1次/d;胞二磷胆碱0.5~1g+5%葡萄糖250mL,1次/d;对症治疗。治疗组40例通栓活络汤(半夏、白术各15g,石菖蒲20g,陈皮15g,川芎、桃仁各20g,红花10g,水蛭8g,地龙15g),1剂/d,水煎300mL,早晚口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、中医证候、神经系统症状体征、不良反应。连续治疗2疗程,判定疗效。结果]临床疗效、中医证候、神经功能缺损改善疗效治疗组优于对照组(P0.01)。结论]通栓活络汤联合西药治疗痰瘀阻络型缺血性中风疗效满意。

Tong Hua Adjustable Soup Combined Western Medicine Treatment of Phlegm and Blood Stasis Resistance Type Complex Random Parallel Control Study of Ischemic Stroke

Objective ] To observe the tong chuan adjustable soup treatment of phlegm and blood stasis resistance type complex curative effect of isehemic stroke. Methods ] Using random parallel control method, 80 cases of hospitalized patients in clinic order Numbers simple random divided into two groups. The control group,40 cases of ozagrel sodium 80 mg/times, 1 / d, lg d;Aspirin enteric-coated metformin hydrochloride, 100 mg/times, 1 / d ; Cytidine diphosphate choline 0.5 - 1 g ＋ 5% glucose of 250 m, 1 / d;Symptomatic treatment. Treatment group （ 40 cases of tong chuan adjustable soup （ pinellia, atractylodes each 15 g, including 20 g, 15 g dried tangerine or orange peel, rhizoma ligustici wallichii, each 20 g peach kernel, safflower, 10 g 8 g leech, earthworm 15 g）, 1 / d, Fried 300 ml water, morning and evening oral;Western medicine treatment with the control group. Continuous treatment of 30 d for 1 course of treatment. Observation of clinical symptoms, syndromes, neurological symptoms and signs, adverse reactions. Continuous treatment 2 period of treatment, judge curative effect. Result ] The clinical curative effect, Chinese medicine syndrome, nerve function defect to improve curative effect of treatment group is better than that of control group （ P 〈 0.01 ） . Tong hua loose soup combined western medicine therapy. Conclusion ] The phlegm and blood stasis resistance type winding ischemic stroke curative effect is satisfied