枳实导滞丸联合西药治疗糖尿病胃轻瘫随机平行对照研究

目的]观察枳实导滞丸联合西药治疗糖尿病胃轻瘫疗效。方法]使用随机平行对照方法,将60例住院及门诊患者按随机数字表方法随机分为两组,对照组20例西沙比利10mg/次,3次/d,口服,并按糖尿病常规治疗。治疗组40例枳实导滞丸(黄芪30g,焦白术、茯苓各15g,炙甘草6g,枳实10～15g,酒军6～10g,黄芩10g,黄连6g,神曲20g,槟榔10～20g,莱菔子20g,莪术15g,厚朴10～20g,丹参20g)1剂/d,水煎300mL,早、中、晚3次餐前服;西药治疗同对照组。连续治疗4周为1疗程。观测临床症状、空腹血糖、餐后2h血糖及痞满症状积分。连续治疗2疗程,判定疗效。结果]治疗组显效20例,有效16例,无效4例,总有效率90.00%。对照组显效8例,有效6例,无效6例,总有效率70.00%。治疗组临床疗效优于对照组(P<0.05)。空腹血糖、餐后2h血糖改善治疗组优于对照组(P<0.05),痞满症状积分改善治疗组优于对照组(P<0.05)。结论]枳实导滞丸联合西药治疗糖尿病胃轻瘫疗效满意,优于单纯西药治疗,值得推广。

The Citrus Aurantium Daozhi Pill and Western Medicine Treatment of Diabetic Gastroparesis Randomized Controlled Study

Objective] To observe the citrus aurantium Daozhi Pill western medicine treatment of diabetic gastroparesis efficacy.Method] Randomized controlled random number table method,the 60 inpatients and outpatients were randomly divided into two groups,20 cases of cisapride 10mg / 3 times / day,orally,and conventional diabetes treatment.Treatment group,40 cases of the citrus aurantium Daozhi pill(Huangqi 30g,Tiao Baizhu 15g,Zhi Gancao 6g,Zhishi 10~15g,Dahuang 6~10g,Huangqin 10g,Huanglian 6g,Shenqi 20g,Binlang 10~20g,Zhishi 20g,Laifuzi 15g,Houpo 10~20g,Danshen 20g) 1 dose / day,decoction 300mL,early,middle and late 3 times before meals.Western medicine with the control group.Four weeks of continuous treatment for a course of treatment.Observation of clinical symptoms,fasting blood glucose,postprandial of 2hours blood sugar and fullness symptom score.Continuous treatment course,to determine efficacy.Results] treatment group,20 cases markedly effective in 16 cases,4 cases,total effective rate of 90.00%.Control group,8 cases were markedly effective in 6 cases,6 cases,the total effective rate of 70.00%.The clinical efficacy of the treatment group than the control group(P<0.05).Fasting glucose,2 hours postprandial blood glucose to improve the treatment group than the control group(P<0.05),Fullness symptom score improvement in the treatment group than the control group(P<0.05).Conclusion] Citrus aurantium the joint Western medicine treatment Daozhi pill diabetic gastroparesis efficacy satisfaction,better than western medicine alone is worth promoting.