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柴胡疏肝散联合西药治疗反流性食管炎随机平行对照研究
引用本文:郭丽颖. 柴胡疏肝散联合西药治疗反流性食管炎随机平行对照研究[J]. 实用中医内科杂志, 2013, 0(6): 93-94
作者姓名:郭丽颖
作者单位:吉林省敦化市中医院胃镜室,吉林敦化133700
摘    要:[目的]观察柴胡疏肝散联合西药治疗反流性食管炎疗效。[方法]使用随机平行对照方法,将80例门诊患者按随机数字表法分为两组。对照组40例奥美拉唑肠溶胶囊20mg/次,2次/d;莫沙比利5mg/次,3次/d。治疗组40例柴胡疏肝散(海螵蛸、代赭石各30g,柴胡、白芍药各15g,旋覆花、川芎、陈皮、白术、枳壳、香附各12g,延胡索、木香、半夏、砂仁、甘草各10g,黄连8g);1剂/d,水煎400mL,饭前1h或饭后2h服用,早晚口服。西药治疗同对照组。连续治疗56d为1疗程。观测临床症状、胃镜检查、不良反应。连续治疗1疗程,判定疗效。[结果]临床疗效:治疗组治愈23例,显效11例,有效5例,无效1例,总有效率97.50%。对照组治愈17例,显效8例,有效5例,无效10例,总有效率75.00%。治疗组疗效优于对照组(P〈0.05)。胃镜疗效:治疗组治愈18例,显效11例,有效8例,无效3例,总有效率92.50%。对照组治愈12例,显效8例,有效8例,无效12例,总有效率70.00%。胃镜疗效治疗组优于对照组(P〈0.05)。[结论]柴胡疏肝散联合西药治疗反流性食管炎效果显著,值得推广。

关 键 词:反流性食管炎  柴胡疏肝散  奥美拉唑  莫沙比利  胃镜检查  随机平行对照研究

Chaihu Shugansan Combined with Western Medicine Treatment of Reflux Esophagitis Randomized Controlled Study
GUO Liying. Chaihu Shugansan Combined with Western Medicine Treatment of Reflux Esophagitis Randomized Controlled Study[J]. , 2013, 0(6): 93-94
Authors:GUO Liying
Affiliation:GUO Liying;Dunhua City Chinese Medicine Hospital;
Abstract:[Objective]Observed Chaihu Shugansan combined with Western treatment of reflux esophagitis.[Methods]Using randomized controlled method,80 outpatients were randomly divided into two groups. Control group,40 cases of omeprazole enteric-coated capsules 20mg / times,2 times / d;mosapride 5mg / time,3 times /d. Treatment group 40 cases Chaihu Shugansan(Haipiaoxiao,Daizheshi each 30g,Chaihu,Baishaoyao each 15g,Xuanfuhua,Chuangxiong,Chenpi,Baishu,Zhike,Xiangfu each 12g,Yanhusuo,Muxiang,Banxia,Sharen,Gancao each 10g,Huanglian 8g);1 does / d,decoction 400mL,before meals or after meals 1h 2h take,sooner or later orally. Western medicine with the control group. 56d is a course of continuous treatment. Observation of clinical symptoms,endoscopy,adverse reactions. Continuous treatment of a course of treatment,to determine efficacy.[Results]Clinical efficacy:treatment group were cured,23 cases,11 cases markedly effective in 5 cases,1 case,the total effective rate 97.50%. Control group,17 cases were cured,8 cases were markedly effective in 5 cases,10cases,total effective rate 75.00%. Treatment group than the control group(P0.05). Endoscopic therapeutic effect:18 cases were cured,11 cases markedly effective in 8 cases,3 cases,the total efficiency 92.50%. Control group,12cases were cured,8 cases were markedly effective,8 cases,12 cases,the total efficiency of 70.00%. Endoscopic treatment group than the control group effect(P0.05).[Conclusion]CHSGS combined with western medicine treatment of reflux esophagitis effect is significant,worthy of promotion.
Keywords:Reflux esophagitis  Chaihu Shugansan  Omeprazole  Mosapride  Gastroscopy  Randomized controlled study
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