中药联合傣药外敷治疗急性痛风性关节炎随机对照临床研究

目的]探讨中药联合傣药外敷治疗急性痛风性关节炎的临床效果和安全性。方法]选择急性痛风性关节炎患者80例,随机分为治疗组和对照组,每组各40例。在常规给予低嘌呤低脂饮食、患肢制动、碱化尿液基础上,对照组给予消炎痛片25mg/次+碳酸氢钠片0.9g/次,3次/d;治疗组在常规治疗的基础上给予傣药、中药制成的散剂外敷于患处,1次/d。比较两组治疗前、后的临床症状评分和实验室生化指标改善,以及不良反应情况。结果]治疗1周后,两组患者的关节疼痛、肿胀和压痛评分均显著缓解,ESR、UA和CRP等实验室生化指标显著下降(P<0.05),其中治疗组改善程度显著好于对照组(P<0.05)。治疗组治疗总有效率为90.00%,显著高于对照组(P<0.05),且两组患者治疗过程中未见严重的不良反应。结论]中药联合傣药外敷治疗急性痛风性关节炎疗效显著、起效快、安全性高,能显著缓解患者临床症状,改善生化指标,值得临床推广。

Combination of Chinese Traditional Medicine Dai Medicine External Application in the Treatment of Acute Gouty Arthritis Randomized Controlled Clinical Study

Objective]Investigate Dai medicine external application combined with traditional Chinese medicine for treatment of acute gouty arthritis clinical efficacy and safety.Methods]The acute gouty arthritis 80 cases,were randomly divided into treatment group and control group,40 cases in each group.In conventional low purine diet low in fat,limb braking,alkalinization of the urine basis,the control group was given indomethacin tablets 25mg/ + sodium bicarbonate tablets 0.9g/,3 /d;the treatment group was treated with routine therapy was given based on Dai medicine,traditional Chinese medicine powder made from externally applied to the affected area,1 /d.Comparison of the two groups before treatment,after scoring of clinical symptoms and laboratory biochemical improvement,and adverse reaction.Results]After 1 weeks of treatment,the two groups of patients with joint pain,swelling and tenderness scores were significantly relieved,ESR,UA and CRP biochemical index decreased significantly(P < 0.05),the treatment group improved significantly than that in control group(P < 0.05).Treatment group total effective rate was 90,significantly higher than that of control group(P < 0.05),and the two groups of patients during the treatment no severe adverse reaction.Conclusion]Dai medicine external application combined with traditional Chinese medicine for treatment of acute gouty arthritis with obvious curative effect,quick effect,high safety,can significantly relieve clinical symptoms,improvement in the biochemical parameters,worthy of clinical application.