镇肝熄风汤治疗高血压随机平行对照研究

目的]观察镇肝熄风汤治疗高血压疗效。方法]使用随机平行对照方法，将68例门诊患者按就诊时间分为两组。对照组34例苯磺酸氨氯地平片，5mg／,1次／d，口服。治疗组34例镇肝熄风汤（怀牛膝30g，生赭石、生牡蛎各25g，生龙骨20g，生麦芽、茵陈各15g，生龟甲、生白芍、川楝子、天冬、玄参各10g，甘草5g），1剂／d，水煎200mL，早晚口服；耳鸣加蝉蜕15g；恶心、呕吐加半夏lOg；心烦燥热加茯神、山栀子、黄芩各lOg；头晕、头痛加珍珠母30g，石决明20g，夏枯草lOg。连续治疗30d为l疗程。观测临床症状、血压、不良反应。治疗1疗程，判定疗效。结果]治疗组显效2l例，有~r．10例，无效3例，总有效率91．18％。对照组显效17例，有效13例，无效4例，总有效率88．24％。治疗组疗效优于对照组（P〈0．05）。血压两组均有改善（P〈O．05），治疗组改善优于对照组（P〈O．05）。结论j镇肝熄风汤治疗高血压效果显著，值得推广。

Zhenganxifeng Decoction in the Treatment of Hypertension,Randomized Parallel Controlled Study

Objective ] To observe the curative effect of tranquilizing liver wind Decoction in the treatment of hypertension. Methods ] Using randomized controlled methods, 68 patients were divided into two groups. A control group of 34 cases Amlodipine Besylate Tablets, 5mg/, 1 /d, oral. The treatment group of 34 cases of Zhenganxifeng Decoction （ Huainiuxi 30g, Shengzhushi, Shengmuli each 25g, Shenglonggu 20g, Shengmaiya, Yinchen each 15g, Shengguijia, Shengbaishao, Chuanlianzi, Tiandong, Xuanshen each 10g, Gancao 5g ）, 1 doses of/d, water simmer in water 200mL, sooner or later, tinnitus add Chantui 15g; nausea, vomiting add Banxia 10g; upset hot plus Fushen, Shanzhizi, Huangqin each 10g; dizziness, headache add Zhenzhumu 30g, Shijueming 20g, Xiakucao 10g. Continuous treatment with 30d for 1 courses. Observation of clinical symptoms, blood pressure, adverse reaction. 1 courses of treatment, the curative effect. 21 cases of group therapy. Results ] 10 cases were effective, 3 cases ineffective, the total efficiency of 91.18%. The control group was 17 cases, effective 13 cases, invalid 4 cases, the total efficiency of 88.24%. The treatment group was better than control group （ P〈 0.05 ） . The blood pressure of two groups were improved （ P〈 0.05 ）, the treatment group was better than the control group （ P〈 0.05 ） . Conclusion ] Zhenganxifeng Decoction in the treatment of hypertensive effect is significant, worthy of promotion.