龙虎交战针法治疗痛性糖尿病周围神经病变:随机对照研究

目的:比较龙虎交战针法与普瑞巴林胶囊治疗痛性糖尿病周围神经病变的临床疗效。方法:将60例痛性糖尿病周围神经病变患者随机分为观察组和对照组,各30例。在常规降糖、营养神经治疗基础上,观察组于三阴交、足三里、阴陵泉、血海行龙虎交战针法,每日1次;对照组予普瑞巴林胶囊75mg口服,每日2次。2周为一疗程,共治疗2个疗程。比较两组治疗前后疼痛视觉模拟量表(VAS)评分、健康调查简表(SF-36)评分和神经传导速度,并评定两组临床疗效。结果:治疗后两组患者VAS评分均较治疗前下降(P<0.05),观察组VAS评分降低幅度大于对照组(P<0.05);治疗后,两组患者正中神经和胫后神经的感觉神经传导速度(SNCV)、运动神经传导速度(MNCV)均较治疗前提高(P<0.05),观察组高于对照组(P<0.05);治疗后两组患者SF-36各项评分均较治疗前升高(P<0.05),观察组高于对照组(P<0.05)。观察组的总有效率为86.7%(26/30),优于对照组的60.0%(18/30,P<0.05)。结论:龙虎交战针法能缓解痛性糖尿病周围神经病变患者疼痛症状,改善其生存质量,提高神经传导速度,疗效优于口服普瑞巴林胶囊。

Dragon-tiger fighting needling therapy in treatment of painful diabetic peripheral neuropathy:a randomized controlled trial

Objective To compare the clinical therapeutic effect on painful diabetic peripheral neuropathy(PDPN)between dragon-tiger fighting needling and pregabalin capsules.Methods A total of 60 patients with PDPN were randomized into an observation group and a control group,30 cases in each one.On the base of treatment with routine anti-hyperglycaemic measures and nutritional neurotherapy,the dragon-tiger fighting needling was exerted at Sanyinjiao(SP 6),Zusanli(ST 36),Yinlingquan(SP 9)and Xuehai(SP 10)in the observation group,once daily.Pregabalin capsules were prescribed for oral administration in the control group,75 mg,twice a day.The treatment for 2 weeks was as one course and 2 courses of treatment were required in total.The score of visual analogue scale(VAS),the score of MOS item short form health survey(SF-36)and nerve conduction velocity before and after treatment were compared between the two groups.The clinical therapeutic effect was evaluated in the two groups.Results After treatment,VAS score was reduced as compared with before treatment in the two groups(P<0.05).The reducing range of VAS score in the observation group was larger than the control group(P<0.05).After treatment,the sensory nerve conduction velocity(SNCV)and motor nerve conduction velocity(MNCV)of median nerve and posterior tibial nerve were all improved as compared with before treatment in the two groups(P<0.05).SNCV and MNCV in the observation group were higher than the control group(P<0.05).After treatment,the score of each item in SF-36 was increased as compared with before treatment in the two groups(P<0.05)and the score of each item in SF-36 in the observation group was higher than the control group(P<0.05).The total effective rate was 86.7%(26/30)in the observation group,better than 60.0%(18/30)in the control group(P<0.05).Conclusion The dragon-tiger fighting needling therapy relieves painful symptoms,improves the quality of life and increases nerve conduction velocity in the patients with diabetic peripheral neuropathy,and the therapeutic effect is better than oral administration of pregabalin capsules.