艾灸对高血压病患者血压及NO、ET、SOD、MDA的影响

目的:探讨艾灸对高血压病患者血压及血清一氧化氮(NO)、血清内皮素(ET)、血清超氧化物歧化酶(SOD)和血清丙二醛(MDA)的影响.方法:以艾灸百会穴治疗48例高血压病患者,观察治疗前后血压、血清NO、ET、SOD和MDA的变化,并与30例健康对照组进行对比观察.结果:高血压病患者血清NO及SOD水平明显低于健康对照组(P＜0.01),血清ET及MDA水平明显高于健康对照组(P＜0.01);艾灸治疗后可使患者血压明显下降(P＜0.01),血清NO及SOD水平明显上升(P＜0.01);血清ET及MDA水平明显下降(P＜0.01).结论:艾灸治疗高血压病在使患者血压下降的同时,可调节血管内皮细胞的内分泌功能和调节氧自由基(OFR)产生与清除的酶系统.

Effects of moxibustion on blood pressure,NO,ET,SOD and MDA in the patient of hypertension

Objective To explore effects of moxibustion on blood pressure (BP), serum nitric oxide (NO), endothelin (ET), superoxide dismutase (SOD) and malodialdehyde (MDA) in the patient of hypertension. Methods Moxibustion was given at Baihui (GV 20) in 48 cases of hypertension, and changes of BP, serum NO, ET, SOD and MDA before and after treatment were investigated, with 30 healthy persons used as controls. Results Serum NO and SOD in the patient of hypertension were significantly lower, and ET and MDA were higher than those in the control group (all P<0.01); after treatment BP and serum ET and MDA significantly decreased (all P<0.01), and serum NO and SOD increased (P<0.01). Conclusion Moxibustion can decrease blood pressure and regulate endocrine function of vascular endotheliocytes and the enzyme system of producing and scavenging oxide free radicals.