头部电针透穴治疗脑卒中后抑郁症临床观察

目的:研究头部电针透穴疗法治疗脑卒中后抑郁症(PSD)的临床疗效及作用机理。方法:108例PSD患者随机分为电针透穴组(38例)、非透穴组(36例)和西药组(34例)。电针透穴组选用悬颅透悬厘、脑户透强间、头临泣透阳白等穴;非透穴组选用百会、印堂、四神聪等穴;西药组采用氟西汀口服。治疗28天后,分别对3组疗效、治疗前后HAMD抑郁量表评分、SDS自评量表评分和血浆中5-羟色胺(5-HT)含量进行对比观察。结果:电针透穴组有效率为86.84%,明显优于非透穴组的63.89%和西药组的67.65%(P<0.01,P<0.05)。电针透穴组能明显提高血浆中5-HT含量,与非透穴组相比差异有非常显著性意义(P<0.01),与西药组相比差异有显著性意义(P<0.05)。结论:头部电针透穴疗法能明显提高病人血浆中5-HT含量,治疗PSD的疗效明显优于非透穴组和西药组。

Clinical observation on head point-through-point electroacupuncture for treatment of poststroke depression

Objective To observe clinical therapeutic effect of head point-through-point electroacupuncture(EA)on poststroke depression(PSD)and to study the mechanism.Methods One hundred and eight cases of PSD were randomly divided into a point-through-point EA group(n=38),a non point-through-point group(n=36)and a western medicine group(n=34).After treatment of 28 days,their therapeutic effects,scores of HAMD depression scale and SDS self-rating scale,and plasma 5-HT contents were compared before and after treatment among the 3 groups.Results The effective rate of 86.84% in the point-through-point EA group was better than 63.89% in the non point-through-point group and 67.65% in the western medicine group(P<0.05 or P<0.01).Plasma 5-HT content in the point-through-point EA group increased significantly,with a very significant difference as compared with that of the non point-through-point group(P<0.01).Conclusion Head point-through-point therapy can obviously increase plasma 5-HT content of the patient with PSD,so as to cure poststroke depression,with a better thera-peutic effect than other two groups.