序贯疗法治疗中风病偏瘫及对患者血浆ET-1、NO的影响

目的：观察序贯疗法治疗中风病偏瘫的临床疗效，并探讨其作用机理。方法：将144例中风病偏瘫患者随机分为序贯疗法组（治疗组）和传统针刺组（对照组）各72例。治疗组根据患者处于软瘫期、痉挛期、相对恢复期、后遗症期选取不同的穴位，对照组统一采用常规取穴。治疗3个月后观察临床疗效，检测患者血浆内皮素（ET-1）、一氧化氮（NO）水平。结果：治疗组在改善患者神经功能缺损程度、总的生活能力状态、临床综合疗效、促进康复进程及降低血浆ET—1、升高NO水平等方面优于对照组（P〈0．05，P〈0．01），且病程越短，疗效越佳。结论：序贯疗法治疗中风病偏瘫疗效显著，能降低血浆ET-1、升高NO水平，为治疗中风病偏瘫的有效疗法。

Sequential acupuncture method for treatment of apoplexy hemiplegia and its effects on plasma ET-1 and NO levels

Objective To observe clinical therapeutic effect of sequential acupuncture method on apoplexy hemiplegia and to probe into the mechanism.Methods One hundred and forty-four cases of apoplexy hemiplegia were randomly divided into a treatment group treated with sequential acupuncture method and a control group treated with traditional acupuncture,72 cases in each group.After treatment for 3 months,their clinical therapeutic effects were observed and plasma endothelin-1(ET-1)and nitric oxide(NO)levels were detected.Results The treatment group in the improvement of the nerve function-deficiency,total life ability and clinical overall effect,and the course of recovery,decreasing of ET-1 level and increasing of NO level was superior to the control group(P<0.05,P<0.01),the shorter the course,the better the therapeutic effect.Conclusion The sequential acupuncture method has an obvious therapeutic effect on apoplexy hemiplegia,and it can decrease plasma ET-1 level and increase NO level.It is an effective therapy for apoplexy hemiplegia.