穴位埋线治疗阿尔茨海默病临床观察

目的：观察穴位埋线治疗阿尔茨海默病（AD）的临床疗效。方法：将26例轻中度AD患者按配对方法分为穴位埋线组和穴位刺激组，穴位埋线组分别在神门、丰隆、太溪和足三里进行埋线，穴位刺激组用相同操作方法刺激穴位，但埋线针不穿入羊肠线，每个月治疗1次，共治疗6次。运用神经心理学量表对2组治疗前后进行评分，并对结果进行统计分析。结果：穴位埋线组治疗后评分与治疗前评分比，简易精神状态量表（MMSE）治疗后评分较治疗前评分显著升高（P〈0．01），阿尔茨海默病认知评价量表（ADAS-Cog）治疗后评分较治疗前评分显著降低（P〈0．01），日常生活能力量表（ADL）治疗前后评分比较差异无显著性意义（P〈0．05）。2组治疗后评分比较，穴位埋线组MMSE评分显著高于穴位刺激组（P〈0．01），穴位埋线组ADAS-Cog评分比穴位刺激组显著性降低（P〈0．05），2组治疗后ADL评分比较差异无显著性意义。结论：穴位埋线提高了AD痴呆患者认知能力及病人的依从性，为针灸治疗老年痴呆提供了新的方法。

Clinical observation on catgut implantation at acupoint for treatment of Alzheimer′s disease

OBJECTIVE: To observe clinical therapeutic effect of catgut implantation at acupoint on Alzheimer's disease (AD). METHODS: Twenty-six cases with mild-moderate AD were divided into an acupoint catgut implantation group and a control group by sample-paired method. The acupoint catgut implantation group were treated with cat-gut implantation at Shenmen (HT 7), Zusanli (ST 36), Fenglong (ST 40) and Taixi (KI 3), and the control group with the same manipulation at the same acupoints with no catgut implanted, once each month, for 6 months. Mini-Mental State Examination (MMSE), Activity of Daily Living (ADL) and Alzheimer's Disease Assessment Scale-Cognitive Section (ADAS-Cog) scores were recorded before and after treatment and analyzed statistically. RESULTS: After treatment, the score of MMSE significantly increased (P < 0.01), the score of ADAS-Cog significantly decreased (P < 0.01) and the score of ADL did not significantly change in the acupoint catgut implantation group; compared with the control group, the score of MMSE in the acupoint catgut implantation significantly increased (P < 0.01), the score of ADAS-Cog significantly decreased (P < 0.05) and the score of ADL did not significantly change in the acupoint catgut implantation. CONCLUSION: Acupoint catgut implantation therapy increases cognitive function of the patient of AD, which provides a new therapeutic method for aged AD.