针刺中脘治疗消化性溃疡：多中心随机对照研究

目的:验证针刺中脘穴治疗消化性溃疡的有效性及安全性。方法:入选病例276例,随机分为针刺组与对照组。针刺组138例,选用中脘穴,长针深刺;对照组138例,口服泰胃美,共观察6周,通过临床症状及胃镜疗效两方面进行疗效观察。结果:针刺组对于快速改善胃脘疼痛及食少的症状效果明显优于对照组(P<0·05)。针刺组总有效率为90·6%,对照组总有效率为88·4%,针刺组疗效略优于对照组,但考虑中心效应,组间疗效无差异(P>0·05)。随着时间推移,两组症状均改善明显(P<0·01),但组间疗效无差异(P>0·05);两组胃镜疗效比较无差异(P>0·05)。结论:针刺中脘穴治疗消化性溃疡疗效可靠,值得临床推广应用。

Multicentral randomized controlled trials of acupuncture at Zhongwan (CV 12) for treatment of peptic ulcer

Objective To evaluate the efficacy and safety of acupuncture at Zhongwan (CV 12) for treatment of peptic ulcer. Methods Two hundred and seventy-six cases enrolled were randomly divided into an acupuncture group and a control group, 138 cases in the acupuncture group were treated with deep needling at Zhongwan (CV 12) with a long needle, and 138 cases in the control group were treated with climetidine. The therapeutic effects were evaluated by clinical symptoms and gastroscopy. They were investigated for 6 weeks. Results The acu-puncture group was better than the control group in rapid alleviation of stomachache and improvement of appetite ( P<0.05 ). The total effective rate was 90.6% in the acupuncture group and 88.4% in the control group with no significant difference ( P>0.05 ). The symptoms improved significantly in the two groups ( P<0.01 ), but with no significant difference between the two groups ( P>0.05 ). There was no significant difference between the two groups in the therapeutic effect of gastroscopy ( P>0.05 ). Conclusion Acupuncture at Zhongwan (CV 12) has a reliable therapeutic effect on peptic ulcer.