首页 | 本学科首页   官方微博 | 高级检索  
     

针刺对肥胖大鼠海马组织一氧化氮含量和一氧化氮合酶活性的影响
引用本文:刘志诚,孙凤岷,朱苗花,孙志,张中成,洪承忖,魏群利. 针刺对肥胖大鼠海马组织一氧化氮含量和一氧化氮合酶活性的影响[J]. 中国针灸, 2003, 23(1): 19-27
作者姓名:刘志诚  孙凤岷  朱苗花  孙志  张中成  洪承忖  魏群利
作者单位:1. 南京中医药大学,江苏,210029
2. 南京人口管理学院
基金项目:国家自然科学基金资助项目(No.39970923)
摘    要:目的:探讨针刺对肥胖大鼠海马组织一氧化氮(NO)含量和一氧化氮合酶(NOS)活性的影响。方法:观察针刺治疗前后肥胖大鼠体重,体脂及海马组织NO含量和NOS活性的变化。结果:肥胖大鼠体重,体脂及海马组织NO含量和NOS活性均显著高于正常大鼠水平;大鼠海马组织NO含量和NOS活性与体重和Lee's指数高度正相关。针刺治疗取得良好减肥疗效。同时,肥胖大鼠海马组织NO含量和NOS活性明显回降。结论:海马组织NO含量和NOS活性异常可能是肥胖发病因素之一;针刺对肥胖机体海马组织NO含量和NOS活性的良好调整作用。可能是实现减肥效应的中枢作用机制之一。

关 键 词:肥胖 大鼠 海马 一氧化氮 针刺疗法 一氧化氮合酶
文章编号:0255-2930(2003)01-0052-03
修稿时间:2002-06-03

Effects of acupuncture on contents of nitric oxide and nitric oxide synthase in the hippocampus in the obese rat
Liu Thicheng,Sun Fengmin,Zhu Miaohua,et al.. Effects of acupuncture on contents of nitric oxide and nitric oxide synthase in the hippocampus in the obese rat[J]. Chinese acupuncture & moxibustion, 2003, 23(1): 19-27
Authors:Liu Thicheng  Sun Fengmin  Zhu Miaohua  et al.
Abstract:Objective To study effect of acupuncture on the content of nitric oxide (NO) and the activity of nitric oxide synthase (NOS) in the hippocampus of the obese rat. Methods The changes of body weight, body fat, and content of NO and activity of NOS in the hippocampus before and after acupuncture were observed. Results The body weight, body fat, and the content of NO and the activity of NOS in the hippocampus all were significantly higher than those in the normal rat; there were high positive correlation of the levels of NO and activities of NOS in the hippocampus with the body weight, Lee's index; after acupuncture treatment, the marked weight reduction effect was achieved, and the level of NO and the activity of NOS in the hippocampus decreased significantly. Conclusion Abnormal levels of NO and activities of NOS in the hippocampus may be an important factor for obesity; the benign regulation of acupuncture on the level of NO and the activity of NOS in the hippocampus is possibly one of the central nervous mechanisms of reducing body weight.
Keywords:Acupuncture  Obesity  Hippocampus/chem  Nitric Oxide/anal  Nitric Oxide Synthase*
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《中国针灸》浏览原始摘要信息
点击此处可从《中国针灸》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号