热针配合中药离子导入联合西药治疗类风湿关节炎疗效观察

目的:探讨提高西药治疗类风湿关节炎(RA)疗效的治疗方案。方法:将96例RA患者随机分为综合组(48例)和西药组(48例)。综合组采用热针电针治疗仪,穴取上肢肩、曲池、手三里、支沟;下肢风市、阳陵泉、梁丘、膝阳关等,配合中药离子导入、口服西药美洛昔康、柳氮磺胺吡碇、甲氨喋呤治疗;西药组单纯西药治疗。2组的疗程均为1个月。观察2组治疗前后晨僵时间、握力、压痛关节数、肿胀关节数等临床症状、体征的变化情况;观察治疗前后血中类风湿因子(RF)、C-反应蛋白(CRP)、血沉(ESR)、白细胞计数(WBC)和血小板计数(PLT)等指标的变化情况。结果:综合组有效率为79.2%,西药组有效率为52.1%,综合组的疗效优于西药组(P<0.01)。治疗1个月后,2组患者的晨僵时间、双手平均握力、关节压痛和关节肿胀均有明显改善(P<0.01),且综合组优于西药组(P<0.01)。2组治疗后血中RF、CRP、ESR、WBC和PLT等指标均有下降(P<0.01),且综合组血中CRP、ESR、PLT的下降较西药组明显(P<0.01)。结论:热针配合中药离子导入联合西药治疗类风湿关节炎疗效优于单纯药物治疗。

Observation on therapeutic effect of heat needle combined with herb iontophoresis and western medicine on rheumatoid arthritis

Objective To search for a therapeutic program for increasing the therapeutic effect of western medicine on rheumatoid arthritis(RA).Methods Ninety-six cases of RA were randomly assigned to a treatment group and a control group,48 cases in each group.The treatment group were treated with heat electroacupuncture instrument with Chinese herb iontophoresis,combined with Meloxicam,Salazosulfamide,and Methotrexate.The control group with simple the western medicine.After treatment of a month,changes of the morning stiff duration,grasp strength,number of tenderness joints,tenderness index,joint rest pain,number of swelling joints,swelling index,assessment of the patient and doctor,and blood rheumatism factor(RF),C-response protein(CRP),erythrocyte sedimentation rate(ESR),the white blood cell(WBC) and platelet counts(PLT) were investigated.Results The effective rate was 79.2% in the treatment group and 52.1% in the control group,the treatment group being significantly better than the control group(P<0.01).After treatment of one month,morning stiff duration,average grasp strength of the both hands,tenderness of joint and swelling of joints significantly improved(P<0.01),with the treatment group being superior to the control group(P<0.01).After treatment,blood RF,CRP,ESR,WBC and PLT decreased in the two groups(P<0.01),and the decreases of blood CRP,ESR,PLT in the treatment group were more significantly as compared with the control group(P<0.01).Conclusion The therapeutic effect of heat needle combined with herb iontophoresis and western medicine is superior to simple medicine for treatment of rheumatoid arthritis.