解郁调神针刺法治疗失眠伴抑郁障碍疗效观察

目的:比较解郁调神针刺法与口服曲唑酮(美抒玉)治疗失眠伴抑郁障碍患者的疗效差异。方法:将65例患者随机分为针刺组(33例)和西药组(32例)。针刺组穴取神门、百会、印堂、合谷、太冲,每天1次针刺治疗;西药组服用曲唑酮(美抒玉),每天1次,共服4周。采用匹兹堡睡眠质量指数评定量表(PSQI)、抑郁自评量表(SDS)和Asberg副作用量表(SERS)进行疗效对比。结果:针刺组愈显率为72.7%(24/33),优于西药组的46.8%(15/32);两组患者治疗后PSQI各项评分、总分,SDS评分均较治疗前明显降低(P0.01,P0.05),其中针刺组在睡眠质量和日间功能评定方面较西药组降低更明显(均P0.05)。治疗后西药组Asberg副作用量表评分显著高于针刺组(P0.05)。结论:解郁调神针刺法可改善失眠患者睡眠质量和日间功能,且优于口服曲唑酮,不良反应较小。

Effect of acupuncture treatment of relieving depression and regulating mind on insomnia accompanied with depressive disorders

Objective: This paper observed the effect of the soothing liver and regulating mind acupuncture method in treating patients of insomnia with depressive disorder. Take Trazodone (Mesyrel) as the positive control drug, compare the effect difference of these two methods while treating this disease, and discuss the mechanism of the soothing liver and regulating mind acupuncture in dealing with insomnia. Method: Observed 65 cases of insomnia with depressive disorder and divide into two groups with randomized method. One is acupuncture group used soothing liver and regulating mind needling, the other is control drug group (Trazodone). One course is composed of 4 weeks. Use Pittsburg Sleep Quality Index Rating Scale (PSQI), Self-rating Depressive Scale (SDS), and Asberg Side-effect Rating Scale (SERS) to compare the effects. Result: The comparisons of each item and total score of PSQI of the patients in soothing liver and regulating mind acupuncture group and western drug group before and after treatment have significant differences (P＜0.01). The comparison of the total scores of PSQI between groups have no significant difference (P＞0.05), while soothing liver and regulating mind acupuncture group is better than those of western medicine group at the aspects of sleep quality and daytime functional assessment, and the scores of the other items of the two groups are proximal (P＞0.05). Before and after the treatment, the scores of self-rating depressive scale(SDS) of patients of both groups were obviously lowered (P＜0.01), but the comparison of the SDS scores of the patients of the two groups after treatment has no obvious statistical difference (P＞0.05).Conclusion: Soothing liver and regulating mind acupuncture method has curative effects on insomnia with depressive disorder, and soothing liver and regulating mind acupuncture group is better than those of Trazodone group on sleep quality and daytime functional assessment. The side-effect of soothing liver and regulating mind acupuncture is less than that of western medicine (Trazodone).