| 针刺对实验性急性癫痫大鼠脑干—γ—氨基丁酸和谷氨酸含量的影响 |
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| 引用本文： | 闫丽萍,李建军.针刺对实验性急性癫痫大鼠脑干—γ—氨基丁酸和谷氨酸含量的影响[J].中国针灸,1999,19(4):235-237. |
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| 作者姓名： | 闫丽萍 李建军 |
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| 作者单位： | 陕西中医学院(闫丽萍)，中山医科大学孙逸仙纪念医院(李建军) |
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| 摘 要： | 采用马桑内酯（ＣＬ）３５ｍｇ／ｋｇ给大鼠肌注造成急性癫痫大发作模型，选用督脉“百会”和肝经郄穴“中都”，针治组用泻法，针防组用平补平泻法，并与正常组和模型组对照。结果针刺可明显降低癫痫大鼠脑干谷氨酸（ＧＬＵ）水平，提高针防组γ氨基丁酸（ＧＡＢＡ）与ＧＬＵ比值。说明针刺可通过影响氨基酸类递质来防治癫痫。
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| 关 键 词： | 癫痫／针灸疗法 脑干／化学 γ-氨基丁酸类／分析 谷氨酸 |
Effectds of Acupuncture on Contents of r Aminobutyric Acid and Glutamic Acid in the
Brain Stem of Rats of Acute Experimental Epilepsy |
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| Yan Liping,Li Jianjun ,et al..Effectds of Acupuncture on Contents of r Aminobutyric Acid and Glutamic Acid in the
Brain Stem of Rats of Acute Experimental Epilepsy[J].Chinese Acupuncture & Moxibustion,1999,19(4):235-237. |
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| Authors: | Yan Liping Li Jianjun |
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| Institution: | Yan Liping,Li Jianjun 1,et
al. |
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| Abstract: | Acute severe epilepsy rat model
was developed by intermuscular injection of 3.5mg/kg coriamyrtin and Baihui point on
the Du Channel and Zhongdu point on the Liver Channel were selected.Reducing method
was used in the acupuncture treatment group and the uniform reinforcing reducing
method was used in the acupuncture prevention group.Results indicated that acupuncture
reduced obviously level of glutamic acid (Glu) and increased ratio of of r aminobutyric
acid and Glu in the brain stem of rats with epilepsy,It is suggested that acupuncture
prevents and treats epilepsy through influencing amino acid transmitters. |
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| Keywords: | EPILEPSY/acup ther BRAIN STEM/chem AMINOBUTYRIC ACIDS/anal GLUTAMATE |
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