| 针刺对脑萎缩模型小白鼠脑细胞核蛋白及染色质非组蛋白的影响 |
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| 引用本文： | 石学敏,韩景献.针刺对脑萎缩模型小白鼠脑细胞核蛋白及染色质非组蛋白的影响[J].中国针灸,1999,19(1):43-46. |
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| 作者姓名： | 石学敏 韩景献 |
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| 作者单位： | 天津中医学院第一附属医院 |
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| 摘 要： | 采用聚丙烯酰胺凝胶电泳（ＳＤＳ－ＰＡＧＥ），观察了针刺“水沟”、“内关”穴后，快速老化脑萎缩模型小白鼠（ＳＡＭ－Ｐ／１０）脑细胞核蛋白质及染色质ＮＨＣＰ的电泳图谱，经光密度扫描仪扫描，测定蛋白区带峰面积比值。结果显示，针刺可以降低膜蛋白（细胞核蛋白中分子量为６２ＫＤ的蛋白区带）含量；增加非组蛋白（染色质蛋白中分子量为２４ＫＤ的蛋白区带）含量。研究表明，针刺“水沟”、“内关”穴对一些蛋白质在衰老过程中出现的增龄性变化具有拮抗作用。
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| 关 键 词： | 核蛋白类／针灸效应 染色质／针灸效应 脑疾病／针灸疗法 萎缩／针灸疗法 |
Effects of Acupuncture on Nucleoproteins and Chromatinic Nonhistone of Brain Cells in
Mice of Encephalatrophy |
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| Shi Xuemin,Han Jingxian,Zhao Junhong,et al.Effects of Acupuncture on Nucleoproteins and Chromatinic Nonhistone of Brain Cells in
Mice of Encephalatrophy[J].Chinese Acupuncture & Moxibustion,1999,19(1):43-46. |
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| Authors: | Shi Xuemin Han Jingxian Zhao Junhong et al |
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| Abstract: | olyacrylamide gel electrophoresis was used for investigation on
electrophoretogram of nucleoprotiens and chromatinic nonhistone of brain cells in the
mice of rapid aging encephalatrophy(SAM P/10) after acupuncture of Shuigou(GV26) and
Neiguan(PC 6) Scaining for optical density and determination of the peak area ratio of
protein zones indicated that acupuncture decreased the content of membrance protein(the
protein zone of 62 KD molecular weight in cellular nucleoproteins) and increased the
content of nonhistone(the protein zone of 24 KD molecular weight in chromatinic
proteins) It is suggested that acupuncture of Shuigou and Neiguan points have
antagonistic action on the change of some proteins in senile process |
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| Keywords: | NUCLEOPROTEINS/acup eff CHROMATIN/acup eff BRAIN DISEASES/acup ther ATROPHY/acup ther |
| 本文献已被 CNKI 维普 等数据库收录！ |
