| 电针对局灶性脑缺血大鼠兴奋性氨基酸含量的影响 |
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| 引用本文： | 许能贵,马勤耘.电针对局灶性脑缺血大鼠兴奋性氨基酸含量的影响[J].中国针灸,1999,19(7):431-432. |
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| 作者姓名： | 许能贵 马勤耘 |
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| 作者单位： | 安徽中医学院针灸经络研究所，广州中医药大学 |
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| 基金项目： | 国家自然科学基金,国家中医药管理局科研基金 |
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| 摘 要： | 采用凝闭大鼠大脑中动脉致局灶性脑缺血模型，研究脑缺血区脑组织Ｇｌｕ、Ａｓｐ的含量。结果显示，缺血６０ｍｉｎ后，脑组织Ｇｌｕ、Ａｓｐ升高均有非常显著性意义（Ｐ＜０．０１）。提示ＥＡＡ（Ｇｌｕ、Ａｓｐ）参与缺血区神经元的损害。电针督脉经“百会”、“大椎”２穴１０ｍｉｎ后，可有效地降低脑组织中Ｇｌｕ、Ａｓｐ的含量，阻止神经元继发性坏死，将为临床针灸治疗缺血性中风提供理论依据。
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| 关 键 词： | 电针 脑缺血／针灸疗法 天冬氨酸／分析 谷氨酸钠／分析 |
Effect of Electroacupuncture on Levels of Excitatory Amino Acids in Rats of Focal Cerebral Ischemia |
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| Xu Nenggui,Ma Qinyun,Hou Siwei.Effect of Electroacupuncture on Levels of Excitatory Amino Acids in Rats of Focal Cerebral Ischemia[J].Chinese Acupuncture & Moxibustion,1999,19(7):431-432. |
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| Authors: | Xu Nenggui Ma Qinyun Hou Siwei |
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| Abstract: | Contents of glutamic acid(Glu)and aspartic acid(Asp) of the brain tissue in ischemic area were investigated in the rats of focal cerebral ischemis induced by coagulation of middle cerebral artery. Result showed that after 60 minutes of ischemia,Glu and Asp contents in the brain tissue had very significant increases( P <0 01),suggesting that excitatory amino acids(Glu and Asp)are involved in injury of neurons in the ischemic area.While electroacupunture at Baihui(GV 20)and Dazhui(GV 14)points for 10 minutes could reduce effectively the contents of Glu and Asp in the brain tissue, preventing secondary necrosis of neurons,which supply a theoretical basis for clinical acupuncture and moxibustion treatment of ischemic apoplexy. |
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| Keywords: | CEREBRAL ISCHEMIA/acup ther ELECTROACUPUNCTURE ASPARTIC ACID/anal SODIUM GLUTAMATE/anal |
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