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原发性高脂血症中医证型与客观指标相关性研究
引用本文:娄彦梅,李峰,霍艳明,王玉光,倪量.原发性高脂血症中医证型与客观指标相关性研究[J].中华中医药杂志,2010(4).
作者姓名:娄彦梅  李峰  霍艳明  王玉光  倪量
作者单位:北京中医药大学基础医学院;北京中医药大学东方医院;北京地坛医院;
基金项目:“十一五”重大专项(No.2008ZX10005-003);;国家重点基础研究发展计划(973)中医理论研究专项资助课题(No.2005CB523506)~~
摘    要:目的:探讨高脂血症中医证型规律及与年龄、性别、体质量指数(BMI)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-胆固醇(LDL-C)、高密度脂蛋白-胆固醇(HDL-C)、载脂蛋白ApoAI、ApoB的相关性。方法:对120例原发性高脂血症患者进行中医辨证分型,运用Logistic回归分析对客观指标和中医证型的相关性进行对照分析,探讨其相关性。结果:回归分析显示原发性高脂血症的中医证型与血脂指标、年龄、性别、BMI之间有一定的相关性。结论:痰浊阻遏证与脾肾阳虚证为主要证型,原发性高脂血症的中医证型与年龄、性别、体质量指数、血脂指标之间有一定的相关性,可以考虑为中医辨证分型客观化提供理论基础。脾肾亏虚、痰瘀互结是原发性高脂血症的重要病机。辨治上以健脾益肾、益气养心、活血化痰为法,取得了很好的效果。

关 键 词:原发性高脂血症  中医证型  血脂指标  Logistic回归分析  

Research on associativity of TCM syndrome and objective indexes of primary hyperlipemia
LOU Yan-mei,LI Feng,HUO Yan-ming,WANG Yu-guang,NI Liang.Research on associativity of TCM syndrome and objective indexes of primary hyperlipemia[J].China Journal of Traditional Chinese Medicine and Pharmacy,2010(4).
Authors:LOU Yan-mei  LI Feng  HUO Yan-ming  WANG Yu-guang  NI Liang
Institution:1School of Preclinical Medicine;Beijing University of Chinese Medicine;Beijing 100029;China;2Dongfang Hospital;Beijing 100078;3Beijing Ditan Hospital;Beijing 100011;China
Abstract:Objective: To probe into TCM pattern of primary hyperlipemia and its relationship with gender, age, BMI, laboratory indices such as TC,TG, LDL-C, HDL-C, ApoAI, ApoB of the 120 patients with primary hyperlipemia. Methods: Logistic regression analysis wan used to analyze the associativity of TCM syndrome and objective indexes of primary hyperlipemia. Results: Logistic regression analysis showed that TCM syndromes of primary hyperlipemia had some relation with laboratory indices. Conclusion: TCM syndromes of p...
Keywords:Primary hyperlipemia  TCM syndrome  Indexes of blood lipids  Logistic regression analysis  
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