| 苍柏湿毒清颗粒使支原体耐药菌株产生敏感化趋势以及与白介素IL-2、IL-12的相关性研究 |
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| 引用本文： | 蔡玲玲,李元文,张丰川,孙占学,周志强,赵雅静,杨勇智.苍柏湿毒清颗粒使支原体耐药菌株产生敏感化趋势以及与白介素IL-2、IL-12的相关性研究[J].中华中医药杂志,2012(1):175-178. |
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| 作者姓名： | 蔡玲玲 李元文 张丰川 孙占学 周志强 赵雅静 杨勇智 |
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| 作者单位： | 北京中医药大学;北京中医药大学东方医院皮肤科 |
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| 基金项目： | 国家中医药管理局中医药科学技术研究专项课题(No.06-07LP06)~~ |
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| 摘 要： | 目的:通过临床疗效观察和实验指标检测探讨苍柏湿毒清作用机制,探求解脲支原体感染优化的治疗方案。方法:将患者随机分为01组(苍柏湿毒清颗粒)、02组(左氧氟沙星)、03组(苍柏湿毒清颗粒+左氧氟沙星),比较症候积分和检测实验指标。结果:①有效率:03组69.70%01组33.33%02组45.45%。02组耐药率54.55%,复发率33.33%。②血清白介素IL-2、IL-12变化:01组03组02组。结论:①中药合用抗生素复发率低,并且使耐药菌株有敏感化趋势。中西医结合治疗模式为最优化的治疗方案。②中药与IL-2、IL-12变化存在相关性。
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| 关 键 词： | 苍柏湿毒清颗粒 耐药性 敏感化趋势 白细胞介素- 白细胞介素- |
Study of the Cangbai Shiduqing Granule making azithromycin-resistant Uu strain sensitive to azithromycin and the relationship with blood IL-2,IL-12 |
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| CAI Ling-ling,LI Yuan-wen,ZHANG Feng-chuan,SUN Zhan-xue,ZHOU Zhi-qiang,ZHAO Ya-jing,YANG Yong-zhi.Study of the Cangbai Shiduqing Granule making azithromycin-resistant Uu strain sensitive to azithromycin and the relationship with blood IL-2,IL-12[J].China Journal of Traditional Chinese Medicine and Pharmacy,2012(1):175-178. |
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| Authors: | CAI Ling-ling LI Yuan-wen ZHANG Feng-chuan SUN Zhan-xue ZHOU Zhi-qiang ZHAO Ya-jing YANG Yong-zhi |
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| Institution: | CAI Ling-ling1,LI Yuan-wen2,ZHANG Feng-chuan2,SUN Zhan-xue2,ZHOU Zhi-qiang2,ZHAO Ya-jing2,YANG Yong-zhi1(1Beijing University of Chinese Medicine,Beijing 100029,China;2Department of Dermatology,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China) |
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| Abstract: | Objective: We want to find potential mechanism of Cangbai Shiduqing Granule through clinical observations and compared various lab results,and make better treatment plans.Methods: We randomly divided patients who fit our requirements into 3 groups,group 01 treated with Cangbai Shiduqing Granule,group 02 treated with Levofloxacin,group 03 treated with both.We compared TCM syndrome scores and test Lab results.Results: ①Efficacy rates: group 03 is 69.70%,group 01 is 33.33%,group 02 is 45.45%.Drug resistance rate: group 02 is 54.55%.Recurrence rate: group 02 is 33.33%.②Blood IL-2,IL-12 values: group 01>gruop 03>group 02.Conclusion: ①The hightest efficacy and lowest reccurence is the combined Cangbai Shiduqing Granule with Levofloxacin method which is the best recently and make resistant Uu strain have trendency of susceptibility.②Cangbai Shiduqing Granule is related to Blood IL-2,IL-12. |
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| Keywords: | Cangbai Shiduqing Granule Drug resistant Trendency of susceptibility Blood interleukin-2 Blood interleukin-12 |
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