六味地黄丸合生脉胶囊对高血压患者心脏保护作用

目的:观察口服六味地黄丸合生脉胶囊对心肾(气阴)两虚型原发性高血压心脏保护作用。方法:采用开博通降压的同时,口服六味地黄丸和生脉胶囊治疗原发性高血压55例,并设对照组对照,疗程1年观察患者血压(BP)、心脏功能、心肌肥厚和血管内皮损伤程度。结果:治疗组治疗后多项指标显著下降,与对照组比较有显著差异(P<0.05)。结论:口服六味地黄丸和生脉胶囊与开博通有协同降压作用,能降低心肾(气阴)两虚高血压患者心肌耗氧指数,逆转心肌肥厚,改善左心室功能,保护血管内皮,防止动脉硬化,对高血压所致心脏损害有明显保护作用。

Protective effect of Liuweidihuang pill combined with Shengmai capsule on heart of patients with hypertension

To observe the protective e ect of oral Liuweidihuang pill combined with Shengmai capsule on heart of primary hypertension with syndrome of de ciency of both qi and yin of heart and kidney.Method:While decreasing blood pressure with Captopril,oral Liuweidihuang pill combined with Shengmai capsule was used to treat 55 cases of primary hypertension,control groups was established.BP,cardiac function,damage degree of myocardial hypertrophy and blood vessel endothelium were detected.Result:ALL the indexes above in treatment group decreased obviously,showed signi cant di erence when compared with control group.Conclusion:Oral Liuweidihuang pill combined with Shengmai capsule and Captopril has cooperative e ect of antihypertension.The combined medication can treat heart damage by reducing myocardial oxygen consumption index,reversing myocardial hypertrophy,improving left ventricular function,protecting blood vessel endothelium,and preventing arteriosclerosis.