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血小板及纤溶活性与糖尿病肾病中医辨证分型关系研究
引用本文:唐红,徐蓉娟,李红,杨华,葛芳芳.血小板及纤溶活性与糖尿病肾病中医辨证分型关系研究[J].上海中医药杂志,2003,37(7):18-20.
作者姓名:唐红  徐蓉娟  李红  杨华  葛芳芳
作者单位:上海中医药大学附属龙华医院内分泌科,上海,200032
摘    要:为研究血小板及纤溶活性改变与糖尿病肾病(DN)关系。选择健康对照组(A组)30例,2型糖尿病无血管病变组(B组)30例,2型糖尿病并发糖尿病肾病气阴两虚型(C组)41例、气虚血瘀型(D组)42例,分别测定血浆CD62p、CD63、组织型纤溶酶原激活物(t-PA)、组织型纤溶酶原激活物抑制物(PAI)。结果显示:气虚血瘀型患者CD62p、CD63、PAI明显升高,t-PA明显下降。提示血小板及纤溶活性改变与DN关系密切,并为DN中医辨证分型及治疗提供客观依据。

关 键 词:血小板  纤溶活性  糖尿病肾病  辨证分型  中医
文章编号:1007-1334(2003)07-0018-03
修稿时间:2003年2月1日

Correlation Between Platelet and Fibrinolysin Activity and Chinese Medical Syndromes of Diabetic Nephrosis
TANG Hong XU Rong,juan LI Hong,YANG Hua GE Fang,fang,Longhua Hospital Affiliated to Shanghai University of TCM.Correlation Between Platelet and Fibrinolysin Activity and Chinese Medical Syndromes of Diabetic Nephrosis[J].Shanghai Journal of Traditional Chinese Medicine,2003,37(7):18-20.
Authors:TANG Hong XU Rong  juan LI Hong  YANG Hua GE Fang  fang  Longhua Hospital Affiliated to Shanghai University of TCM
Institution:TANG Hong XU Rong juan LI Hong YANG Hua GE Fang fang Longhua Hospital Affiliated to Shanghai University of TCM
Abstract:To study the correlation between platelet and fibrinolysin activity and Chinese medical syndromes of diabetic nephrosis(DN),plasma CD 62P ,CD 63 ,t PA and PAI respectively in 30 healthy people,in 30 cases of type 2 diabetes absent from vascular diseases,in 41 cases of DN of qi yin deficiency,and in 42 cases of qi deficiency and blood stasis.Results showed,in the patients with qi deficiency and blood stasis,that CD 62P ,CD 63 and t PA increased obviously,and PAI reduced remarkably.It is revealed that platelet and fibrinolysin activity have close relationship with DN,which provides objective evidence for its differentiation and treatment.
Keywords:Diabetic nephrosis  CD    62P  CD    63  t  PA  PAI  syndrome differentiation
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