| 芦丁对3T3-L1前脂肪细胞分化的作用 |
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| 引用本文： | 张伟云,王青,向云亚,温忠秀,陈全成.芦丁对3T3-L1前脂肪细胞分化的作用[J].上海中医药杂志,2018,52(1):90-94. |
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| 作者姓名： | 张伟云 王青 向云亚 温忠秀 陈全成 |
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| 作者单位： | 厦门医学院中心实验室厦门市中药生物工程重点实验室福建省中药精加工与健康产品开发重点研究室福建省道地药材生物工程重点实验室厦门医学院药学系;厦门大学药学院 |
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| 基金项目： | 国家自然科学基金面上项目(81773601)；福建省教育厅2015年第二批高等学校优秀学科(专业)带头人赴海外访学研修资助项目；福建省自然科学基金计划资助项目(项目编号:2015J01065)；福建省卫生系统中青年骨干人才培养项目2015年资助计划基础项目、厦门市卫计委资助项目(2015-ZQN-JC-45)；厦门市科技局科技计划高校创新项目(3502Z20143026)；厦门市科技局科技计划项目(3502Z20144031)；厦门医学院科研项目(Z2013-12,Z2013-25) |
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| 摘 要： | 目的探索芦丁对3T3-L1前脂肪细胞分化的影响。方法采用3T3-L1前脂肪细胞分化模型和油红O染色法,选用罗格列酮作为阳性对照药,观察芦丁对3T3-L1前脂肪细胞分化的作用,于510 nm波长下测定芦丁对脂含量的影响。利用流式细胞仪测定芦丁对分化的脂肪细胞吸收葡萄糖的影响。结果芦丁在0.5μmol/L和1μmol/L两个浓度下均能促进3T3-L1前脂肪细胞分化过程,提高脂含量,并促进了葡萄糖吸收。结论芦丁能够促进3T3-L1前脂肪细胞分化,并促进了分化的脂肪细胞吸收葡萄糖。
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| 关 键 词： | 芦丁 3T3-L1前脂肪细胞 分化 糖吸收 |
| 收稿时间： | 2017/10/10 0:00:00 |
Effects of rutin on differentiation of 3T3-L1 preadipocytes |
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| ZHANG Weiyun,WANG Qing,XIANG Yuny,WEN Zhongxiu and CHEN Quancheng.Effects of rutin on differentiation of 3T3-L1 preadipocytes[J].Shanghai Journal of Traditional Chinese Medicine,2018,52(1):90-94. |
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| Authors: | ZHANG Weiyun WANG Qing XIANG Yuny WEN Zhongxiu and CHEN Quancheng |
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| Institution: | Central Laboratory of Xiamen Medical College Xiamen Key Laboratory of Biotechnology of Chinese Traditional Medicine Fujian Provincial Key Laboratory of Traditional Chinese Medicine Finish Processing and Health Products Development Fujian Provincial Key Laboratory of Genuine Regional Drug Bioengineering Department of Pharmacy, Xiamen Medical College, Xiamen 361023, China,Central Laboratory of Xiamen Medical College Xiamen Key Laboratory of Biotechnology of Chinese Traditional Medicine Fujian Provincial Key Laboratory of Traditional Chinese Medicine Finish Processing and Health Products Development Fujian Provincial Key Laboratory of Genuine Regional Drug Bioengineering Department of Pharmacy, Xiamen Medical College, Xiamen 361023, China,Central Laboratory of Xiamen Medical College Xiamen Key Laboratory of Biotechnology of Chinese Traditional Medicine Fujian Provincial Key Laboratory of Traditional Chinese Medicine Finish Processing and Health Products Development Fujian Provincial Key Laboratory of Genuine Regional Drug Bioengineering Department of Pharmacy, Xiamen Medical College, Xiamen 361023, China,Central Laboratory of Xiamen Medical College Xiamen Key Laboratory of Biotechnology of Chinese Traditional Medicine Fujian Provincial Key Laboratory of Traditional Chinese Medicine Finish Processing and Health Products Development Fujian Provincial Key Laboratory of Genuine Regional Drug Bioengineering Department of Pharmacy, Xiamen Medical College, Xiamen 361023, China and School of Pharmaceutical Sciences, Xiamen University, Xiamen 361102, China |
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