补化汤对气虚血瘀型急性脑梗死患者血小板体积异常影响的临床研究

为探讨中医药治疗气虚血瘀型急性脑梗死 (ABI)的临床疗效及其对血小板体积异常的影响 ,将 6 5例患者随机分为治疗组 (中药补化汤加常规治疗组 ) 34例和对照组 (常规治疗组 ) 31例。治疗 2周后观察患者神经功能评分以及血小板体积分布宽度 (PDW )、平均血小板体积 (MPV )、大型血小板比率 (P -LCR)的变化情况。结果 :两组患者神经功能的变化均有显著性意义(P <0 0 0 1 ) ;治疗组PDW、MPV、P -LCR治疗前后有显著性差异 (P <0 0 0 1 ) ,对照组无明显变化 (P >0 0 5 )。提示 :中医药对ABI血小板体积异常有明显的改善作用。

Clinical Study of "Buhua Decoction" on Platelet Size Abnormality in Patients with Acute Cerebral Infarction of Qi-Deficiency and Blood-Stasis Syndrome

To explore the clinical effects of Chinese medicine in the treatment of acute cerebral infarction of qi-deficiency and blood-stasis syndrome and its mechanism, 65 subjects were randomized into two groups: treatment group in which 34 cases were treated with the Decoction and routine western medications and control group in which 31 cases were treated with routine western medications. After 2-week treatment, clinical effects were evaluated in accordance with nerve function scale; the platelet distribution width (PDW), median platelet volume (MPV) and large platelet ratio (P-LCR) were measured in two groups. Results: There were great differences in the nerve functions between two groups (P<0.001); PDW, MPV and P-LCR improved after treatment in treatment group (P<0.001), no improvement in control group. It is revealed that Chinese medicine is quite effective in improving platelet size in patients with acute cerebral infarction.