| 化瘀克塞方对急性脑梗死患者神经元特异性烯醇化酶变化的影响 |
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| 引用本文： | 陈家权,李长生,杨晓妮.化瘀克塞方对急性脑梗死患者神经元特异性烯醇化酶变化的影响[J].上海中医药杂志,2009,43(3):17-19. |
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| 作者姓名： | 陈家权 李长生 杨晓妮 |
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| 作者单位： | 陈家权,CHEN Jia-quan(山东大学医学院2006级研究生,山东,济南,250012);李长生,杨晓妮,LI Chang-sheng,YANG Xiao-ni(山东大学附属千佛山医院中医科,山东,济南,250014)
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| 摘 要： | 目的观察化瘀克塞方对急性脑梗死患者神经元特异性烯醇化酶（NSE）变化的影响。方法将70例急性脑梗死症状发生后48h内入院的患者随机分为化瘀克塞方组（37例）和常规治疗组（33例）,分别于入院后即时和治疗后的第3、7、14天清晨空腹抽取静脉血测定NSE的浓度,同时进行神经功能缺损评分。结果化瘀克塞方组和常规治疗组患者入院时血清NSE浓度显著高于正常对照组（P〈0.05）,两组患者之间差异无统计学意义（P〉0.05）;治疗第3天、第14天两组患者NSE浓度差异无统计学意义（P〉0.05）,治疗第7天化瘀克塞方组患者血清NSE浓度显著低于常规治疗组（P〈0.05）。两组患者在治疗第3天后神经功能缺损评分即较入院时明显改善（P〈0.05）;治疗第7天、第14天时,组间同期神经功能缺损评分比较,差异有统计学意义（P〈0.05）。结论化瘀克塞方能够有效降低急性脑梗死患者血清NSE浓度及神经功能缺损评分,减轻脑损害,对急性脑梗死有神经保护作用。
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| 关 键 词： | 脑梗死 中西医结合疗法 化瘀克塞方 神经元特异性烯醇化酶 神经功能缺损评分 |
Effects of "Huayu Kesai Decoction" on Serum Neuron-Specific Enolase in Acute Cerebral Infarction Patients |
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| CHEN Jia-quan LI Chang-sheng YANG Xiao-ni.Postgraduate of Medical College,Sh,ong University.Effects of "Huayu Kesai Decoction" on Serum Neuron-Specific Enolase in Acute Cerebral Infarction Patients[J].Shanghai Journal of Traditional Chinese Medicine,2009,43(3):17-19. |
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| Authors: | CHEN Jia-quan LI Chang-sheng YANG Xiao-niPostgraduate of Medical College Sh ong University |
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| Institution: | CHEN Jia-quan1 LI Chang-sheng2 YANG Xiao-ni21.Postgraduate of Medical College,Sh,ong University2.Qianfoshan Hospital Affiliated to Sh,ong University |
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| Abstract: | Objective To observe the effects of "Huayu Kesai Decoction" on serum neuron-specific enolase(NSE) in patients with acute cerebral infarction.Methods Seventy patients with acute cerebral infarction hospitalized within 48 hours after onset were randomized into two groups: treatment group in which 37 cases received "Huayu Kesai Decoction" treatment and control group in which 33 cases received conventional treatment.Fasting venous blood samples were collected on days 0,3,7 and 14 after hospitalization to detect... |
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| Keywords: | Cerebral infarction integrative Chinese & western medicine "Huayu Kesai Decoction" neuron-specific enolase neurological impairment scale |
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