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胆腑舒胶囊对实验性胆囊结石胆汁卵磷脂、总胆汁酸、黏蛋白及血清脂代谢的影响
引用本文:龙明照,龙凤昌,钱靖,贾云,马湖蕊,宋云娟.胆腑舒胶囊对实验性胆囊结石胆汁卵磷脂、总胆汁酸、黏蛋白及血清脂代谢的影响[J].中国中医基础医学杂志,2001,7(7):28-29.
作者姓名:龙明照  龙凤昌  钱靖  贾云  马湖蕊  宋云娟
作者单位:云南省红十字会医院中西医结合科,
基金项目:云南省卫生厅青年科研基金资助项目(No.98001)
摘    要:目的:观察胆腑舒胶囊对家兔实验性胆固醇结石的作用及机制。方法:血清脂代谢指标在全自动生化仪上完成,胆汁中总胆固醇、总胆汁酸分别用硫磷铁法、磷钼酸比色法测定,胆汁中卵磷脂、黏2蛋白分别运用硝化-磷钼酸-氨萘磺酸法、磷钨酸沉淀-酚试剂法测定。结果:胆腑舒胶囊可有效降低血清TC、TG、LDL-C及胆汁中胆固醇、黏蛋白浓度,提高胆汁中总胆汁酸,卵磷脂含量。结论:胆碎舒胶囊能较好溶、排胆囊胆固醇结石,其机制与调节脂质代谢,改善致石性胆汁及纠正胆囊动力学等作用有关。

关 键 词:胆腑舒胶囊  胆囊胆固醇结石  脂代谢  卵磷脂  总胆汁酸  黏蛋白
文章编号:1006-3250(2001)07-0028-03
修稿时间:2000年9月5日

Effect of DanFuShu capsule on bile lecithin,total bile acid, mucin and serum lipid metabolism in experimental gallstone rabbits
LONG Ming zhao,LONG Fengchang,QIAN Jing,et al..Effect of DanFuShu capsule on bile lecithin,total bile acid, mucin and serum lipid metabolism in experimental gallstone rabbits[J].Chinese Journal of Basic Medicine In Traditional Chinese Medicine,2001,7(7):28-29.
Authors:LONG Ming zhao  LONG Fengchang  QIAN Jing  
Abstract:Objective To observe the effect of DanFuShu capsule on Experimental gallstone Rabbits and study the mechanism.Methods lipid metabolism with active biochemical instrumental method.Bile cholesterol and total bile acid with nemafos method and phosphomolybdate colorimetry method individually.Bile lecithin and mucin with nitrification phosphomdybdate naphthionic acid method and phosphotungstic acid precipitaion phenol reagent method individually.Results DanFuShu capsule can obviously reduce serum TC,TG,LDL C and bile cholesterol,mucin,increase total bile acid and lecithin content in bile.Conclusions DanFuShu capsule has good effect to gallstone,the mechanism is related to regulation of lipid metabolism and improvement of pathological bile and gallbladder dynamics.
Keywords:Gallstone  Lipid metabolism  Bile lecithin and total bile acid and mucin  DanFuShu capsule
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