针刺对局灶性脑缺血大鼠脑血流量的影响

目的：观察电针督脉经大椎、百会2穴对脑缺血后神经元损伤的保护作用。方法：选择凝团大鼠一侧大脑中动脉致局灶性脑缺血为模型，采用氢气清除法测量缺血区局部脑血流量（rCBF）为指标。结果：①缺血组在脑缺血10分钟、60分钟、120分钟后，rCBF均显著下降；②在缺血加电针组中，给予电针治疗10分钟后，rCBF迅速恢复，和缺血相比，差异有非常显著性意义（P＜0．01）；和假手术对照组相比，差异无显著性意义（P＞0．05）。结论：电针能够迅速改善脑缺血后缺血区局部脑血流量，从而保护神经元缺血性损伤。

The Influence of Acupuncture on Cerebral Blood Flow of Rats with Focal Cerebral Ischemia

Objective:To observe the protective effect electrical a cupuncture of Dazhui(DU 14) and Baihui(DU 20)on the damage of neuron after cerebral ischemia. Methods:The focal cerebral ischemia rat model was established by occlusion of unilateral middle cerebral artery. The cerebral blood flow ischemic area was measured by hydrogen-clearance method.Results:1.In ischemic group,after cerebral ischemia for 10 min,60 min and 120 min,the local cerebral blood flow was markedly decreased.2.In ischemic group treated with electrical acupuncture,the local cerebral blood flow restored rapidly 10 min after treatment,the difference being very singnicant(P<0.01).But the difference was not significant(P>0.05)as compared with the control group (pseudo-operation group).Conclusion:The electrical acupuncture can rapidly improve the local cerebral blood flow after cerebral ischemia,so as to prevent the damage of neuron.