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芩术四物汤乙酸乙酯萃取部位化学成分研究
引用本文:袁海梅,彭腾,黄道秋,李小年,李柏群,凌智群,杨菁,贺钢民,黎豫川.芩术四物汤乙酸乙酯萃取部位化学成分研究[J].中国实验方剂学杂志,2013,19(3):136-139.
作者姓名:袁海梅  彭腾  黄道秋  李小年  李柏群  凌智群  杨菁  贺钢民  黎豫川
作者单位:成都中医药大学药学院教育部中药材标准化重点实验室中药资源系统研究与开发利用省部共建 国家重点实验室培育基地,成都 610075;成都中医药大学药学院教育部中药材标准化重点实验室中药资源系统研究与开发利用省部共建 国家重点实验室培育基地,成都 610075;重庆三峡中心医院药剂科,重庆 万州 404000;中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;重庆三峡中心医院药剂科,重庆 万州 404000;成都中医药大学药学院教育部中药材标准化重点实验室中药资源系统研究与开发利用省部共建 国家重点实验室培育基地,成都 610075;成都中医药大学药学院教育部中药材标准化重点实验室中药资源系统研究与开发利用省部共建 国家重点实验室培育基地,成都 610075;成都中医药大学药学院教育部中药材标准化重点实验室中药资源系统研究与开发利用省部共建 国家重点实验室培育基地,成都 610075;成都中医药大学药学院教育部中药材标准化重点实验室中药资源系统研究与开发利用省部共建 国家重点实验室培育基地,成都 610075
基金项目:重庆市科委重点项目(CSTC2011AC5141);四川省教育厅重点课题(09ZA028);四川省教育厅重点课题(10ZA095);成都市科技局科技攻关项目(10GGYB303SW-023);成都中医药大学校基金重点课题(ZRZD201101)
摘    要:目的:研究芩术四物汤乙酸乙酯萃取部位的化学成分。方法:利用硅胶柱色谱和凝胶等分离操作进行分离、纯化,通过理化性质和波谱特征鉴定结构。结果:从芩术四物汤乙酸乙酯萃取部位中分离鉴定了14个化合物,分别为棕榈酸甘油酯(1),2(S)-5,7-二羟基-6-甲氧基二氢黄酮(2),β-谷甾醇(3),5,7-二羟基-8-甲氧基黄酮(4),白杨素(5),苯甲酸(6),白术内酯-Ⅲ(7),反式阿魏酸(8),7-羟基-4’-甲氧基异黄酮(9),黄芩苷元(10),5,7,3’,6’-四羟基-8,2’-二甲氧基黄酮(11),3,5,7,2’,6’-五羟基二氢黄酮(12),5,7,2’,6’-四羟基黄酮(13),没食子酸(14)。结论:14个化合物均首次从芩术四物汤复方中分离得到。

关 键 词:芩术四物汤  中药复方  黄酮类  化学成分
收稿时间:2012/9/19 0:00:00

Chemical Constituents from the Ethyl Acetate Extract Parts of Qinzhu Siwu Tang
YUAN Hai-mei,PENG Teng,HUANG Dao-qiu,LI Xiao-nian,LI Bo-qun,LING Zhi-qun,YANG Jing,HE Gang-min and LI Yu-chuan.Chemical Constituents from the Ethyl Acetate Extract Parts of Qinzhu Siwu Tang[J].China Journal of Experimental Traditional Medical Formulae,2013,19(3):136-139.
Authors:YUAN Hai-mei  PENG Teng  HUANG Dao-qiu  LI Xiao-nian  LI Bo-qun  LING Zhi-qun  YANG Jing  HE Gang-min and LI Yu-chuan
Institution:Pharmacy College, Chengdu University of Traditional Chinese Medicine; the Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine; State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Chengdu 610075, China;Pharmacy College, Chengdu University of Traditional Chinese Medicine; the Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine; State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Chengdu 610075, China;Pharmacy Department of Sanxia Central Hospital in Wanzhou, Chongqing 404000, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;Pharmacy Department of Sanxia Central Hospital in Wanzhou, Chongqing 404000, China;Pharmacy College, Chengdu University of Traditional Chinese Medicine; the Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine; State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Chengdu 610075, China;Pharmacy College, Chengdu University of Traditional Chinese Medicine; the Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine; State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Chengdu 610075, China;Pharmacy College, Chengdu University of Traditional Chinese Medicine; the Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine; State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Chengdu 610075, China;Pharmacy College, Chengdu University of Traditional Chinese Medicine; the Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine; State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources, Chengdu 610075, China
Abstract:
Keywords:Qinzhu Siwu Tang  traditional Chinese medicine  compouds  flavonoids  chemical constituents
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