| 补阳还五汤治疗中风的系统综述/Meta分析的方法学质量评价 |
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| 引用本文： | 翁湘涛,胡伟雄,周倩仪,张诗静,李绍烁,陈新林.补阳还五汤治疗中风的系统综述/Meta分析的方法学质量评价[J].中国实验方剂学杂志,2016,22(14):217-221. |
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| 作者姓名： | 翁湘涛 胡伟雄 周倩仪 张诗静 李绍烁 陈新林 |
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| 作者单位： | 广州中医药大学 第二临床医学院, 广州 510405,广州中医药大学 第三临床 医学院, 广州 510405,广州中医药大学 第一临床医学院, 广州 510405,广州中医药大学 第二临床医学院, 广州 510405,广州中医药大学 第二临床医学院, 广州 510405,广州中医药大学 基础医学院, 广东 广州 510006 |
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| 基金项目： | 国家自然科学基金项目（81403296）；广东省医学科研基金项目（B2013163）；广州中医药大学“薪火计划”项目（XH20140105）；广州中医药大学省级大学生创新创业训练计划项目（201410572055） |
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| 摘 要： | 目的:评价补阳还五汤对比其他干预方法治疗中风的系统综述/Meta分析的方法学质量。方法:检索中国生物医学期刊网,维普,万方,中国知网,Cochrane图书馆数据库,纳入补阳还五汤对比其他干预方法治疗中风的系统综述/Meta分析的文献,检索时限截至2015年5月。采用Oxman-Guyatt Overview Assessment Questionnaire(OQAQ)量表对纳入文献进行评价。结果:共检索到92篇文献,最终纳入9篇文献,纳入的Meta分析主要存在以下问题:文献检索不全面、选择性偏倚控制不佳、原始文献方法学质量评价不标准、数据合并方法和前提准确性不高。原始文献实验设计存在以下缺陷:随机方法不明、没有开展分组隐蔽及盲法、没有报告意向性分析和不良反应事件、控制玷污或联合干扰描述不详细等。结论:近年来国内外补阳还五汤治疗中风的系统评价/Meta分析的文献逐渐增多,但能够达到高质量的系统评价/Meta分析较少,需进一步提高方法学水平和规范实验设计。
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| 关 键 词： | 补阳还五汤 中风 系统评价 方法学质量评价 |
| 收稿时间： | 2015/9/27 0:00:00 |
Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke |
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| WENG Xiang-tao,HU Wei-xiong,ZHOU Qian-yi,ZHANG Shi-Jing,LI Shao-shuo and CHEN Xin-lin.Methodological Quality Assessment in Systematic Review/Meta Analysis of Buyang Huanwu Tang in Treatment of Stroke[J].China Journal of Experimental Traditional Medical Formulae,2016,22(14):217-221. |
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| Authors: | WENG Xiang-tao HU Wei-xiong ZHOU Qian-yi ZHANG Shi-Jing LI Shao-shuo and CHEN Xin-lin |
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| Institution: | Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine (TCM), Guangzhou 510405, China,Third Clinical Medical College, Cuangzhou University of TCM, Guangzhou 510405, China,First Clinical Medical College, Guangzhou University of TCM, Guangzhou 510405, China,Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine (TCM), Guangzhou 510405, China,Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine (TCM), Guangzhou 510405, China and School of Basic Medical Science, Guangzhou University of TCM, Guangzhou 510006, China |
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| Abstract: | Objective: To evaluate the methodological quality of the systematic review/Meta-Analysis (SR/MA) of Buyang Huanwu Tang in treatment of stroke by comparing with other interventions. Method: CMCC, Wanfang China National Knowledge Infrastructure, VIP and Cocranhe databases were searched to select the literature on systematic review/Meta-analysis (SR/MA) of Buyang Huanwu Tang and other interventions in treatment of stroke. The retrieval time limit was up to May 2015.Oxman-Guyatt Overview Assessment Questionnaire (OQAQ) Scale was used to evaluate the methodological and reporting quality of the eligible SR/MA. Result: A total of 92 SR/MA literature were obtained, and 9 of them were finally included. The included Meta analysis literature had the following shortcomings: no comprehensive literature search, high selection bias, poor methodological quality of the original articles, and poor accuracy of data consolidation method and premise. The experimental design of the original articles had the following shortcomings: unclear randomizatioon methods, no grouping concealment, no blinding, no reporting of intent-to-treat (ITT) analysis, uncertain co-intervention and contamination. Conclusion: The number of domestic and overseas literature on SR/MA of Buyang Huanwu Tang in treating stroke is gradually increasing in recent years, but few of them could reach high quality SR/MA, so it is necessary to improve the methodological quality and regulate the experimental design |
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| Keywords: | Buyang Huanwu Tang stroke systematic review Meta-analysis methodological quality assessment |
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