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正交试验优选健胃消食口崩片提取工艺
引用本文:季巧遇,李诒光,刘旭海,乐渝宁.正交试验优选健胃消食口崩片提取工艺[J].中国实验方剂学杂志,2011,17(24):12-15.
作者姓名:季巧遇  李诒光  刘旭海  乐渝宁
作者单位:江中药业股份有限公司,南昌,330029
基金项目:江西省科技厅学术带头人培养计划(2009DD00400)
摘    要:目的:优化健胃消食口崩片的提取工艺。方法:通过正交试验,以橙皮苷提取率、绿原酸提取率和干膏得率为指标,考察加水量、煎煮时间和煎煮次数对提取效果的影响。结果:健胃消食口崩片的最佳提取工艺为煎煮2次,第1次加6倍量水煎煮2 h,第2次加5倍量水煎煮1 h。结论:最佳提取工艺合理、稳定、可行。

关 键 词:健胃消食口崩片  正交试验  提取工艺  橙皮苷  绿原酸
收稿时间:2011/8/30 0:00:00

Optimization of Extraction Technology of Jianwei Xiaoshi Orally Disintegrating Tablet by Orthogonal Test
JI Qiao-yu,LI Yi-guang,LIU Xu-hai and LE Yu-ning.Optimization of Extraction Technology of Jianwei Xiaoshi Orally Disintegrating Tablet by Orthogonal Test[J].China Journal of Experimental Traditional Medical Formulae,2011,17(24):12-15.
Authors:JI Qiao-yu  LI Yi-guang  LIU Xu-hai and LE Yu-ning
Institution:Jiangzhong Pharmaceutical Co. Ltd, Nanchang 330029, China;Jiangzhong Pharmaceutical Co. Ltd, Nanchang 330029, China;Jiangzhong Pharmaceutical Co. Ltd, Nanchang 330029, China;Jiangzhong Pharmaceutical Co. Ltd, Nanchang 330029, China
Abstract:Objective :To optimize extraction technology of Jianwei Xiaoshi orally disintegrating tablet. Method :Orthogonal test was used for optimizing extraction technology of Jianweixiaoshi orally disintegrating tablet with extract yeild of hesperidin, chlorogenic acid and dry extract as indexes. Three factors were investigated including the amount of water, extraction time and extraction times. Result :Optimum extraction technology was as follows: boiled 2 times,first with 6 times amount of water for 2 h and then boiled with 5 times amount of water for 1 h. Conclusion :Optimized technology was reasonable, stable and reliable.
Keywords:Jianwei Xiaoshi orally disintegrating tablet  orthogonal test  extraction technology  heperidin  chlorogenic acid
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