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补肾延年丹对老年大鼠全血细胞DNA修复能力的影响
引用本文:郭语彬,张克纯,徐桂香,刘群良,阳力争,周文泉,张国玺,高普.补肾延年丹对老年大鼠全血细胞DNA修复能力的影响[J].中国实验方剂学杂志,1995,1(2):25-28.
作者姓名:郭语彬  张克纯  徐桂香  刘群良  阳力争  周文泉  张国玺  高普
作者单位:[1]湖南中医学院生化教研室,长沙410007 [2]中国中医研究院西苑医院,北京100091
摘    要:补肾延年丹对老年大鼠全血细胞非程序DNA合成(UDS)的实验结果表明:40秒UF诱导下大鼠全血细胞UDS各组间差异无显著意义(P>0.05),80秒UV诱导下大鼠全血细胞UDS各组间差异有显著意义(P=0.05),补肾延年丹大、中、小剂量组UDS均高于老年空白对照组,说明补肾延年丹能提高老年大鼠对UV损伤时DNA的修复能力。

关 键 词:补肾延年丹  DNA修复能力  非程序DNA合成  实验研究

Effect of Bushen Yanman Granule on DNA Repair Capacity in Whole Blood Cells of Old Rats
Guo Yubin,Zhang Kechun,Xu Guixiang,LiuQunliang,Yang Lizheng,Zhou Wenquan,Zhang Guoxi,Gao Pu.Effect of Bushen Yanman Granule on DNA Repair Capacity in Whole Blood Cells of Old Rats[J].China Journal of Experimental Traditional Medical Formulae,1995,1(2):25-28.
Authors:Guo Yubin  Zhang Kechun  Xu Guixiang  LiuQunliang  Yang Lizheng  Zhou Wenquan  Zhang Guoxi  Gao Pu
Institution:1.Department of Biochemistry,Hunan college of TCM,Changsha 410007;2.Xi yuan Hospital,China Academy of TCM,Beijing 100091
Abstract:The effect of Bushen Yannian granule on unscheduled DNA synthe-ses(UDS)in whole blood cells of old rats was studied. The results showed that UDS in the group treated with Bushen Yannian granule at a high,or moderate,or low dose,was higher than that in the old control group(P<0.05),indicating that it can enhance DNA repair capacity in old rats.
Keywords:DNA Repair capacity  Unscheduled DNA Syntheses  Bushen Yanni- an granule  
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