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健脾补肾方药对大鼠细胞免疫的影响
引用本文:李学林,李建生,吴建成.健脾补肾方药对大鼠细胞免疫的影响[J].中国实验方剂学杂志,1999,5(3):46-48.
作者姓名:李学林  李建生  吴建成
作者单位:河南中医学院第一附属医院(李学林),河南中医学院(李建生),中国科学院上海细胞生物学研究所(吴建成)
摘    要:治疗肿瘤时常采用的化学疗法和放射疗法会加重肿瘤患者已存在的免疫缺陷,降低病人抗肿瘤、抗感染的能力。应用免疫调节剂的肿瘤免疫疗法能调整患者的免疫功能,防止放、化疗对免疫系统的损伤,提高临床治疗效果[1]。中医的健脾补肾法及其方药是提高患者生存质量,减少...

关 键 词:健脾补肾方  细胞免疫  药理学  肿瘤  中医药疗法
收稿时间:1998/10/19 0:00:00

Effect of Recipes of TCM with Strengthening Spleen or Tonifying Kidney on Cellular Immunity in Rats
Li xuelin,Li Jiansheng,Wu Jiancheng.Effect of Recipes of TCM with Strengthening Spleen or Tonifying Kidney on Cellular Immunity in Rats[J].China Journal of Experimental Traditional Medical Formulae,1999,5(3):46-48.
Authors:Li xuelin  Li Jiansheng  Wu Jiancheng
Abstract:In this paper,3 recipes of TCM,strengthening spleen(ss),tonifying kidney(tk)and combination of the two grous(sstk) were studied with immunodificiency rats induced by cyclophosphamide.The results showes that the weights of spleen and thymus were reduced in the model group,after treating the weights of spleen and thymus in these 3 groups were all increased,the level of CD 3,CD 4,CD 8 and CD 25 were decreased while CD 4/CD 8 ratio were increased significantly than those of in the blank control group.Levels of CD 3 and CD 25 in the ss group were higher than in the control group,Levels of CD 3,CD 4,CD 8 and CD 25 in tk and sstk groups were increased remarkably,but the CD 4/CD 8 ratio were lowered in both of the two groups.It is found that every parameters in the two groups were improved and are better than those in the ss group.
Keywords:strengthening spleen  tonifying kidndy  cyclophosphamid  T  lymphocyte subsets
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