桔芩合剂雾化吸入治疗支气管扩张

目的:观察桔芩合剂雾化吸入对支气管扩张的临床疗效。方法:符合痰热壅肺证中医诊断标准的100例支气管扩张患者随机分为对照组、治疗组,每组各50例。对照组予西医常规治疗,治疗组在对照组治疗的基础上加用中药桔芩合剂雾化吸入治疗,疗程均为15 d。分别观察两组治疗前后中医证候积分、临床疗效及肺功能情况。结果:治疗后,两组患者咳嗽气粗、痰多稠黄、痰血咯血、身热口渴、胸脘胀满、舌红苔黄6项证候积分均有不同程度的改善,以治疗组在降低咳嗽气粗、痰多稠黄、胸脘胀满、舌红苔黄积分方面优于对照组,差异有统计学意义(P0.05,P0.01)。治疗组临床疗效有效率为90.00%,对照组为73.47%,治疗组有效率优于对照组(P0.05)。治疗组治疗后肺功能用力肺活量占预计值的百分比(FVC%),第1秒用力呼气容积占预计值的百分比(FEV1%),FEV1/FVC]的改善优于对照组治疗后(P0.05)。结论:桔芩合剂雾化吸入配合常规治疗支气管扩张可提高临床疗效。

Efficacy of Juqin Mixture Aerosol Inhalation Treatment of Bronchiectasis

Objective: The purpose of this study was to evaluate the clinical efficacy of Juqin mixture aerosol inhalation in bronchiectasis patinets. Method: One hundred bronchiectasis patinets with phlegm-heat obstructing lungs were randomly divided into treatment group and control group, with 50 cases each. Both groups were treated with conventional western medication including sputum drainage and short-term use of antibiotics, while Juqin mixture aerosol inhalation was added in the treatment group. The treatment course lasted 15 days. The scores of traditional Chinese medicine syndromes, the therapeutic effect and pulmonary function were observed before and after treatment. Result: After treatment, the syndromes scores including cough wheeze, thick yellow phlegm, hemoptysis or bloody sputum, feel of hot or thirsty, chest epigastric fullness, red tongue with yellowish or greasy fur, were all improved to different degrees in both groups. The scores of symptoms such as cough wheeze, thick yellow phlegm, chest epigastric fullness, red tongue with yellowish or greasy fur in the treatment group were significantly lower than those in the control group (P<0.05, P<0.01). The clinical effective rates were 90.00% in the treatment group, higher than in the control group 73.47% (P<0.05). After treatment, the pulmonary function forced vital capacity(FVC%) predicted values, forced expiratory volume in one second predicted values(FEV_l%) and FEV_l/FVC] improvement in the treatment group was better than in the control group. Conclusion: Juqin mixture aerosol inhalation combined with conventional therapy could significantly improve the clinical efficacy in bronchiectasis.