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蟾蜍类药材化学成分研究进展
引用本文:吴喜燕,高慧敏,王智民.蟾蜍类药材化学成分研究进展[J].中国实验方剂学杂志,2010,16(14):207-214.
作者姓名:吴喜燕  高慧敏  王智民
作者单位:1. 河南中医学院药学院,郑州,450008;中国中医科学院中药研究所,北京,100700
2. 中国中医科学院中药研究所,北京,100700
基金项目:国家自然科学基金,中国中医科学院自选课题 
摘    要:蟾蜍类药材主要包括蟾酥、干蟾、蟾皮和蟾衣,分别是蟾蜍科动物中华大蟾蜍或黑眶蟾蜍的耳后腺或皮肤腺分泌物、干燥全体、表皮及自然褪下的角质衣膜。查阅国内外研究进展,对蟾蜍类药材中化学成分进行分析总结,主要包括蟾蜍二烯羟酸内酯、吲哚生物碱、蟾蜍环酰胺等。

关 键 词:蟾蜍  化学成分  蟾蜍二烯羟酸内酯  吲哚生物碱  蟾蜍环酰胺

Advances on Chemical Constituents in Crude Medicines from Toads
WU Xi-yan,GAO Hui-min and WANG Zhi-min.Advances on Chemical Constituents in Crude Medicines from Toads[J].China Journal of Experimental Traditional Medical Formulae,2010,16(14):207-214.
Authors:WU Xi-yan  GAO Hui-min and WANG Zhi-min
Institution:Pharmacy College, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China;Institue of Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijing 100700, China;Institue of Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijing 100700, China;Institue of Chinese Materia Medica, Academy of Chinese Medical Sciences, Beijing 100700, China
Abstract:Bufonis venenum and bufonis corium have been widely used in the Chinese Traditional Medicine for a long history. To investigate the chemical differences among the bufonis venenum, bufonis corium,and bufonis periostracum, the progress on the chemical constituents in the different medicinal parts from toads, such as venom and skin, was summarized. The chemical constituents mainly included bufadienolides, indole alkaloids, steriods, and etc. More than one hundred bufadienolides and twelve indole alkaliods were reported and 34 references were cited in the present review.
Keywords:toad  chemical constituents  bufadienolides  indole alkaliods  bufogargarizanine
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