| 参苓白术散治疗脾虚型慢性分泌性中耳炎 |
| |
| 引用本文： | 姜胤辉,仝庆忠,陈珊珊,王静,谭秀珍.参苓白术散治疗脾虚型慢性分泌性中耳炎[J].中国实验方剂学杂志,2013,19(13):311-314. |
| |
| 作者姓名： | 姜胤辉 仝庆忠 陈珊珊 王静 谭秀珍 |
| |
| 作者单位： | 齐齐哈尔医学院第一附属医院,黑龙江齐齐哈尔,161041 |
| |
| 摘 要： | 目的:研究参苓白术散对脾虚型慢性分泌性中耳炎患者的治疗作用.方法:随机纳入脾虚型慢性分泌性中耳炎患者60例,分为中西药结合实验组,给予参苓白术散合并考夫克与头孢美特酯治疗；西药对照组仅给予考夫克与头孢美特酯；每组均为30例,并设空白对照组15例,为健康人群.1个疗程(14 d)后用酶联免疫吸附测定(ELISA)法检测各组患者血清白细胞介素(IL)-4,IL-6及干扰素-γ(IFN-γ)浓度变化,并比较各组临床疗效.结果:①实验组临床疗效明显优于对照组(P＜0.05)；②实验组、对照组给药前血清IL-4,IL-6与对照组相比显著升高,IFN-γ显著降低(P＜0.01)；③1个疗程后实验组、对照组血清IL-4,IL-6水平均下调,IFN-γ均上升,实验组均优于对照组(P＜0.05).结论:参苓白术散治疗脾虚型慢性分泌性中耳炎对提高治愈率与改善临床症状方面均有显著效果,其机制可能与改善患者变态反应,调节免疫应答有关.
|
| 关 键 词： | 慢性分泌性中耳炎 脾虚 参苓白术散 变态反应 |
| 收稿时间： | 2012/12/18 0:00:00 |
Clinical Observation on Therapeutic Effect of Shenling Baizhu Powder Treating Chronic Otitis Media with Effusion in Spleen Deficiency Type |
| |
| JIANG Yin-hui,TONG Qing-zhong,CHEN Shan-shan,WANG Jing and TAN Xiu-zhen.Clinical Observation on Therapeutic Effect of Shenling Baizhu Powder Treating Chronic Otitis Media with Effusion in Spleen Deficiency Type[J].China Journal of Experimental Traditional Medical Formulae,2013,19(13):311-314. |
| |
| Authors: | JIANG Yin-hui TONG Qing-zhong CHEN Shan-shan WANG Jing and TAN Xiu-zhen |
| |
| Institution: | First Hospital of Qiqihar Medical School, Qiqihaer 161041,China;First Hospital of Qiqihar Medical School, Qiqihaer 161041,China;First Hospital of Qiqihar Medical School, Qiqihaer 161041,China;First Hospital of Qiqihar Medical School, Qiqihaer 161041,China;First Hospital of Qiqihar Medical School, Qiqihaer 161041,China |
| |
| Abstract: | |
| |
| Keywords: | secretory otitis media spleen deficiency type Shenling Baizhu powder |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
| 点击此处可从《中国实验方剂学杂志》下载免费的PDF全文 |
|
