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| 归芪多糖颗粒制备工艺 | |
| 引用本文： | 陈虎虎,杨金颖,龚苏晓,张铁军,孙静.归芪多糖颗粒制备工艺[J].中国实验方剂学杂志,2012,18(4):32-34. |
| 作者姓名： | 陈虎虎 杨金颖 龚苏晓 张铁军 孙静 |
| 作者单位： | 1. 天津中医药大学,天津300000;天津药物研究院,天津300193 2. 天津中医药大学,天津,300000 3. 天津药物研究院,天津,300193 4. 天津医科大学,天津,300070 |
| 基金项目： | 国家自然科学基金项目(2007BA137B00) |
| 摘 要： | 目的:研究归芪多糖颗粒制剂的成型工艺.方法:以吸湿性、溶解度、成型率为指标,筛选出处方中加入辅料的品种、配比及最佳成型工艺.结果:最佳制粒工艺条件为原料-甘露醇-聚维酮(PVP) 1∶0.9∶0.1,润湿剂为玉米朊乙醇液.结论:颗粒制剂所选辅料合理,成型制备工艺简便可行. |
| 关 键 词： | 归芪多糖 颗粒剂 成型工艺 |
Preparation Technology of Guiqi Polysaccharide Granule |
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| CHEN Hu-hu,YANG Jin-ying,GONG Su-xiao,ZHANG Tie-jun and SUN Jing.Preparation Technology of Guiqi Polysaccharide Granule[J].China Journal of Experimental Traditional Medical Formulae,2012,18(4):32-34. | |
| Authors: | CHEN Hu-hu YANG Jin-ying GONG Su-xiao ZHANG Tie-jun and SUN Jing |
| Institution: | Tianjin University of Traditional Chinese Medicine, Tianjin 300000, China; Tianjin Instiute of Pharmaceutical Research, Tianjin 300193, China;Tianjin University of Traditional Chinese Medicine, Tianjin 300000, China;Tianjin Instiute of Pharmaceutical Research, Tianjin 300193, China;Tianjin Instiute of Pharmaceutical Research, Tianjin 300193, China;Tianjin Medical University, Tianjin 300070, China |
| Abstract: | Objective:To study on forming technology of Guiqi polysaccharide granule.Method:With hygroscopicity,solubility and forming rate as index,kinds and ratio of excipients and optimum forming process of formulation were screened out.Result:Optimum granulating condition:ratio of raw materials-mannitol-PVP was 1∶0.9∶0.1,wetting agent was zein ethanol solution.Conclusion:Selected excipients of granule was reasonable,molding technology was convenient and feasible. |
| Keywords: | Guiqi polysaccharide granule formulation process |
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