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正骨水中徐长卿的提取工艺优化
引用本文:覃葆,李琴,邓欢,蒋文佳,韦东晓,仝丹丹,贺勤. 正骨水中徐长卿的提取工艺优化[J]. 中国实验方剂学杂志, 2013, 19(14): 47-49
作者姓名:覃葆  李琴  邓欢  蒋文佳  韦东晓  仝丹丹  贺勤
作者单位:广西中医药大学, 南宁 530001;广西玉林制药集团有限责任公司, 广西 玉林 537001;广西中医药大学, 南宁 530001;广西中医药大学, 南宁 530001;广西中医药大学, 南宁 530001;广西中医药大学, 南宁 530001;广西中医药大学, 南宁 530001
基金项目:国家科技特派员项目(2009GJE10028)
摘    要:目的: 优选正骨水中徐长卿的提取工艺。 方法: 以丹皮酚提取量为指标,采用正交试验考察粉碎度、乙醇体积分数及提取时间对提取工艺的影响,通过HPLC测定丹皮酚含量。 结果: 最佳提取工艺为粉碎度20目,加70%乙醇浸提60 h,丹皮酚提取量5.34 mg·g-1结论: 该工艺稳定可行,为正骨水的工业生产提供参考。

关 键 词:正骨水  徐长卿  丹皮酚
收稿时间:2012-05-30

Optimization of Extraction Technology for Cynanchum paniculatum in Zhenggu Mixtures
QIN Bao,LI Qin,DENG Huan,JIANG Wen-ji,WEI Dong-xiao,TONG Dan-dan and HE Qin. Optimization of Extraction Technology for Cynanchum paniculatum in Zhenggu Mixtures[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(14): 47-49
Authors:QIN Bao  LI Qin  DENG Huan  JIANG Wen-ji  WEI Dong-xiao  TONG Dan-dan  HE Qin
Affiliation:Guangxi University of Chinese Medicine, Nanning 530001, China;Guangxi Yulin Pharmaceutical Group Co. Ltd, Yulin 537001, China;Guangxi University of Chinese Medicine, Nanning 530001, China;Guangxi University of Chinese Medicine, Nanning 530001, China;Guangxi University of Chinese Medicine, Nanning 530001, China;Guangxi University of Chinese Medicine, Nanning 530001, China;Guangxi University of Chinese Medicine, Nanning 530001, China
Abstract:Objective: To optimize extraction technology of Cynanchum paniculatum in Zhenggu mixtures. Method: With the content of paeonol as index,which was determined by HPLC,effect of grinding degree,ethanol concentration and extraction time on extraction technology was investigated by orthogonal test. Result: Optimum extraction technology conditions were as follows:grinding degree of raw material 20 mesh,maceration extracted 60 h with 70% ethanol,yield of paeonol 5.34 mg·g-1. Conclusion: Optimized technology was stable and feasible,this study could provide a reference for industrial production of Zhenggu mixtures.
Keywords:Zhenggu mixtures  Cynanchum paniculatum  paeonol
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