血府逐瘀汤合小青龙汤治疗慢性肺源性心脏病急性加重期临床观察

目的:探讨血府逐瘀汤合并小青龙汤治疗慢性肺源性心脏病急性加重期临床效果。方法:研究对象选取青海省中医院、青海省红十字医院和西宁市第一人民医院2013年5月—2014年5月联合收治的慢性肺源性心脏病急性加重期患者140例,随机分为对照组,治疗组,各70例;对照组患者采用西医常规治疗,治疗组患者则在对照组治疗基础上加用血府逐瘀汤合小青龙汤治疗;比较两组患者临床疗效,治疗前后中医证候积分,肺通气功能指标,血气分析指标,心功能指标及血液流变学指标等。结果:治疗组患者临床疗效显著优于对照组(P0.05);与治疗前相比,治疗组患者治疗后中医证候积分显著优于对照组(P0.05);治疗组患者治疗后肺通气功能指标和血气分析指标水平均显著优于对照组(P0.05);治疗组患者治疗后心功能指标和血液流变学指标水平均显著优于对照组(P0.05)。结论:血府逐瘀汤合小青龙汤可有效缓解慢性肺源性心脏病急性加重期临床症状体征,提高心肺功能,并有助于改善血液流变学指标。

Xuefu Zhuyu Tang Combined with Xiaoqinglong Tang in Treatment of Acute Exacerbation Stage of Chronic Pulmonary Heart Disease

Objective: To investigate the clinical effects of Xuefu Zhuyu Tang combined with Xiaoqinglong Tang in treatment of elderly patients with acute exacerbation stage of chronic pulmonary heart disease. Method: The 140 patients with acute exacerbation of chronic pulmonary heart disease (COPD) were chosen in the period from May 2013 to May 2014 in Qinghai Hospital of Traditional Chinese Medicine, Qinghai Red Cross Hospital, Xining First People's Hospital, and randomly divided into control group (70 patients) and trentment group (70 patients) with random number table method. Patients in control group received routine western medicine treatment, and the patients in trentment group received additional Xuefu Zhuyu Tang combined with Xiaoqinglong Tang on the basis of treatment in control group. The clinical efficacy, trentment symptom scores, levels of pulmonary function index, blood gas analysis index, cardiac function index and blood rheology index before and after treatment of both groups were compared. Result: The clinical efficacy of trentment group was significantly better than that in control group, with statistically significant difference (P<0.05). The trentment symptom scores in trentment group after treatment were significantly better than those in control group and those before treatment, with statistically significant difference (P<0.05). The levels of pulmonary function index and blood gas analysis index after treatment in trentment group were significantly better than those in control group and those before treatment, with statistically significant difference (P<0.05). The levels of cardiac function index and blood rheology index after treatment in treatment group were significantly better than those in control group and those before treatment, with statistically significant difference (P<0.05). Conclusion: Xuefu Zhuyu Tang combined with Xiaoqinglong Tang in treatment of acute exacerbation stage of chronic pulmonary heart disease can efficiently relieve the clinical symptoms and signs, improve heart and lung functions and help to improve blood rheology index.