| 健脾补肾方联合二甲双胍对肥胖型多囊卵巢综合征患者内分泌及生化指标的影响 |
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| 引用本文： | 翟军,孙莹璞.健脾补肾方联合二甲双胍对肥胖型多囊卵巢综合征患者内分泌及生化指标的影响[J].中国实验方剂学杂志,2011,17(8):247-249. |
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| 作者姓名： | 翟军 孙莹璞 |
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| 作者单位： | 1. 郑州大学第一附属医院,郑州,450052;郑州人民医院妇产科,郑州,450002
2. 郑州大学第一附属医院,郑州,450052 |
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| 摘 要： | 目的:观察健脾补肾方联合二甲双胍对肥胖型多囊卵巢综合征患者内分泌、生化指标的影响。方法:24例肥胖多囊卵巢综合征(PCOS)患者应用二甲双胍500 mg/次,3次/d,同时口服健脾补肾方每日1剂,早晚分服,共3月;20例肥胖PCOS患者单用二甲双胍500 mg/次,3次/d,连续3个月。比较治疗前后临床症状,内分泌和生化指标的改变。结果:治疗后中西医结合组中14例患者恢复了月经,西药组中11例患者恢复了月经。2组患者治疗前后腰臀比(WHR)、促黄体生成素(LH),雄激素(T),空腹胰岛素(FINS),胰岛素曲线下面积(IAUC)明显降低,ISI明显的提高,有显著性差异(P<0.05)。在血脂改善方面,中西医结合组患者治疗后,甘油三酯,低密度脂蛋,载脂蛋白B均明显下降(P<0.05～P<0.01);二甲双胍组患者血脂无明显改变。结论:健脾补肾方联合二甲双胍可明显降低肥胖型多囊卵巢综合征患者LH,T水平,提高胰岛素的敏感性,降低血脂水平,减少二甲双胍副作用,提高患者依从性,尤其是对血脂的改善明显优于单用二甲双胍组。
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| 关 键 词： | 多囊卵巢综合征 二甲双胍 健脾补肾方 |
| 收稿时间： | 2010/12/14 0:00:00 |
Efficacy of Jianpi Bushen Recipe joint Metformin in Endocrine and Biochemical Festures of Obese PCOS Patients |
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| ZHAI Jun and SUN Ying-pu.Efficacy of Jianpi Bushen Recipe joint Metformin in Endocrine and Biochemical Festures of Obese PCOS Patients[J].China Journal of Experimental Traditional Medical Formulae,2011,17(8):247-249. |
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| Authors: | ZHAI Jun and SUN Ying-pu |
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| Institution: | 1*(1.The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450003,China;2.Zhengzhou Peoples’s Hospital,Zhengzhou 450003,China) |
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| Abstract: | Objective:The aim of our study is to assess the effects of Jianpi Bushen recipe joint metformin in endocrine and biochemical festures of Obese polycysticovariansyndrome(PCOS) patients.Method:Twenty-four obsess PCOS patients were administrated metfomin 500 mg three times daily joint Jianpi Bushen recipe one dose of medicine every day,morning and evening hours service for three months.Twenty obsess PCOS patients were administrated metfomin 500 mg three times for three months only.Baseline characteristics were... |
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| Keywords: | polycystic ovary syndrome metformin Jianpi Bushen recipe |
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