芎芷煎方治疗偏头痛62例

目的:观察芎芷煎方治疗偏头痛的临床疗效。方法:将122例偏头痛患者随机分为治疗组(62例)和对照组(60例),治疗组口服中药芎芷煎方,对照组口服西比灵胶囊;2组疗程均为3个月。观察临床疗效和治疗后1,2,3个月头痛发作频率及头痛程度变化情况以及血液流变学指标和颅内动脉平均血流速度变化。结果:治疗组、对照组临床总有效率分别为78.5%,53.2%,组间疗效比较差异有统计学意义(P<0.01);2组治疗后12,,3个月偏头痛发作频率和头痛程度评分均明显降低(P<0.05),组间治疗后同期比较差异均有统计学意义(P<0.05),且治疗组血液流变学指标改善情况和经颅多普勒检查结果与对照组比较也有显著性差异(P<0.05)。结论:芎芷煎方治疗偏头痛具有较好的治疗作用,其作用机制与改善血液微循环有关。

Clinical Observation of Xiongzhi Decoction in Treating 62 Cases of Migraine

Objective: To observe the clinical effects of Xiongzhi decoction on migraine. Method: Total 122 subjects were randomized into two groups:treatment group in which 62 cases were treated with Xiongzhi decoction and control group in which 60 cases were treated with Flunarizine capsule,with a course of 3 months.The clinical efficacy and migraine frequency and severity were observed. Result: The total effective rate was 78.5% in the treatment group and 53.2% in the control group,with a striking difference between them ( P <0.01).After treatment,the scores of migraine frequency and severity were reduced in both groups ( P <0.05),with a significant difference between the two groups ( P <0.05). Conclusion : Xiongzhi decoction is quite effective for migraine.