中药指纹图谱相似度计算方法探析

通过检索CNKI,SCIENCE DIRECT数据库,对近年来出现的中药指纹图谱相似度计算方法进行收集和整理,筛选出20篇相关文献,共共总结出9种相似度计算方法,包括峰重叠率法(Nei系数法)和峰重叠率与共有峰强度结合法(改进Nei系数法)、距离系数法、相关系数和夹角余弦法以及在此基础上作出的改进的其他6种方法。通过分析,各种方法均有各自的优点和缺点,并分析其各自的特点和不足在实际应用过程中应根据需要,以便在实际应用过程中采用恰当的相似度评价方法,使指纹图谱技术更好地应用于中药质量控制。

Study on Similarity Algorithm of Traditional Chinese Medicine Fingerprints

To summarize the similarity algorithm methods used in the analysis of fingerprints for traditional Chinese medicine in recent years through CNKI,SCIENCE DIRECT database retrieval. Twenty articles were found andNinenine kinds of similarity calculation methods were summed up including Nei coefficient and Improved Nei coefficient,distance coefficient,correlation coefficient,cosine of angle and other six improving similarity algorithm methods.The advantages and the advantagesand disadvantages of each method were listed. In practical work, similarity methods should be chosen according to their characteristics, in which way this technique would be applied to the quality control of TCM more appropriately.