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| 柴胡总皂苷提取物体外溶血作用 | |
| 引用本文： | 张国松,封传华,罗晓健,胡鹏翼,肖志强,王跃生.柴胡总皂苷提取物体外溶血作用[J].中国实验方剂学杂志,2011,17(20):166-169. |
| 作者姓名： | 张国松 封传华 罗晓健 胡鹏翼 肖志强 王跃生 |
| 作者单位： | 1. 江西中医学院,南昌,330004 2. 江西中医学院,南昌 330004;中药固体制剂制造技术国家工程研究中心,南昌 330006 3. 江西中医学院,南昌 330004;中国中医科学院中药研究所,北京100700 |
| 基金项目： | 国家重大新药创制专项(2009ZX09103) |
| 摘 要： | 目的:考察柴胡总皂苷提取物的溶血作用和抗氧化剂对柴胡总皂苷溶血的影响。方法:通过肉眼观察和分光光度法考察不同浓度柴胡皂苷的溶血作用及抗氧化剂对柴胡总皂苷溶血的影响。结果:柴胡总皂苷质量浓度为在0.01,0.02 g.L-1时,其溶血曲线呈S形,溶血当量为0.01 mg,溶血指数为1∶10万,抗氧化剂与柴胡总皂苷组溶血率低于同浓度柴胡总皂苷组。结论:柴胡总皂苷具有一定的溶血作用,且溶血强度与浓度呈剂量依赖性,抗氧化剂的加入能减轻柴胡总皂苷的溶血作用。 |
| 关 键 词： | 柴胡总皂苷 体外 溶血作用 |
| 收稿时间： | 2011/3/31 0:00:00 |
Hemolytic Effects of Extraction of Saikosaponins in vitro |
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| ZHANG Guo-song,FENG Chuan-hu,LUO Xiao-jian,HU Peng-yi,XIAO Zhi-qiang and WANG Yue-sheng.Hemolytic Effects of Extraction of Saikosaponins in vitro[J].China Journal of Experimental Traditional Medical Formulae,2011,17(20):166-169. | |
| Authors: | ZHANG Guo-song FENG Chuan-hu LUO Xiao-jian HU Peng-yi XIAO Zhi-qiang and WANG Yue-sheng |
| Institution: | Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China;Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Nanchang 330006, China;Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Nanchang 330006, China;Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China;Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China;Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China |
| Abstract: | |
| Keywords: | saikosaponins in vitro hemolytic |
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