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糖尿病血管并发症的中药防治
引用本文:邬伟魁,张海燕,宋伟,芦乾,刘昊,贺娅,郑琴,杨明.糖尿病血管并发症的中药防治[J].中国实验方剂学杂志,2011,17(19):292-296.
作者姓名:邬伟魁  张海燕  宋伟  芦乾  刘昊  贺娅  郑琴  杨明
作者单位:1. 江西中医学院现代中药制剂教育部重点实验室,南昌 330004;
2. 江西中医学院现代中药制剂教育部重点实验室,南昌 330004;西南交通大学材料先进技术教育部重点实验室,成都610003
3. 江西中医学院现代中药制剂教育部重点实验室,南昌,330004
4. 江西中医学院现代中药制剂教育部重点实验室,南昌 330004;成都中医药大学,成都611137
基金项目:中医药行业科研专项项目(200708006);"十一五"重大新药创制重大专项(2009ZX09103-393,2009ZX09310-005)
摘    要:对糖尿病(diabetes mellitus,DM)血管并发症的中药防治研究进行文献整理和分析。介绍了中药用治微血管并发症(糖尿病性肾病、糖尿病视网膜病变)及中药复方(片剂、注射液、汤剂)、单味药及提取部位(大黄、薏苡仁多糖、苦碟子注射液、山茱萸环烯醚萜总苷)和单体成分(丹酚酸A、葛根素、栀子苷、柚皮苷及黄芪甲苷)在DM大血管并发症防治中的应用研究,包括其临床观察、动物在体研究和体外细胞实验,以期发掘中药在治疗中的优势,为糖尿病治疗的中药应用和新药研发提供参考。在DM血管并发症的治疗药物中,中药因其多成分、多途径、多靶点作用而显示出独特的优势。

关 键 词:糖尿病  消渴  血管并发症  中药
收稿时间:3/2/2011 12:00:00 AM

Effects of Chinese Medicine on Vascular Complication of Diabetes Mellitus
WU Wei-kui,ZHANG Hai-yan,SONG Wei,LU Qian,LIU Hao,HE Y,ZHEN Qin and YANG Ming.Effects of Chinese Medicine on Vascular Complication of Diabetes Mellitus[J].China Journal of Experimental Traditional Medical Formulae,2011,17(19):292-296.
Authors:WU Wei-kui  ZHANG Hai-yan  SONG Wei  LU Qian  LIU Hao  HE Y  ZHEN Qin and YANG Ming
Institution:Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China; Key Lab. of Advanced Technology of Materials (Chinese Education Ministry), Southwest Jiaotong University, Chengdu 610003, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, China; Chengdu University of TCM, Chengdu 611137, China
Abstract:Literatures aboutpreventing vascularcomplication of diabetes mellitus(DM)have beenanalyzed. There aremore and more DM patients with DM vascular complications, which has been paid attention for its big damage.Traditional Chinese medicine shows its characteristics and advantages in DM treatment. Its applicationisgrowing concern. This articlemainlyreviews the traditional Chinese medicine(tablets, injection, decoctions), single herb withextracts(pieplant, coix seed, ect.), and monomer components(salvianolic acid, puerarin, geniposide, naringin and astragaloside)in the prevention and treatment of vascular complications of DM(diabetic nephropathy and diabetic retinopathy), including clinical observations, animal studies in vivo and in vitro experiments.Aiming to explore the advantages of Chinese medicine in the treatmentof DM,andimprove itsapplicationin theresearch of DM and new drug development.
Keywords:diabetes mellitus  vascular complication  traditional Chinese medicine
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