5种贝壳类动物药及其煎出物中微量元素含量测定

目的:测定5种贝壳类饮片及其煎出物中微量元素含量,分析其与功效和毒性的相关性。方法:用等离子发射光谱法、原子荧光法测定Fe,Zn,Mn,Sr,Mg,Cu,Pb,Cd,Hg,As在5种贝壳类药材及煎出物中的含量。用化学滴定法测定钙含量。结果:煅瓦楞子、石决明、蛤壳、珍珠母、紫贝齿药材饮片的平均煎出率分别为2.37%,0.42%,0.38%,0.37%,0.42%,煎出物中的平均钙含量分别为25.85%,13.78%,21.40%,21.42%,13.78%。结论:贝壳类药物经过煎煮富集,煎出物中的微量元素浓度高于饮片。本实验测定的各类贝壳类药材饮片中重金属镉的含量均超出药典标准,建议对该类药材制定科学合理的镉元素限量标准,提高用药安全性。

Determination of Microelement of Testacean Traditional Chinese Medicines

Objective:The content of Ca and microelement in some testacean Chinese traditional medicines and extractions were determined to analyze the correlation of material basis,toxicity and efficacy.Method: The content of Fe,Zn,Mn,Sr,Mg,Cu,Pb,Cd,Hg,As was determined by AES or AFS and Ca was determined by complex-metric titration.Result: The average extraction rates of calcined concha arcae,concha haliotidis,clam shell,concha margaritifera usta and concha cypraeae were 2.37%,0.42%,0.38%,0.37% and 0.42%;the average ...