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中西医结合治疗肺炎喘嗽(痰热壅肺证)的多中心临床研究
引用本文:曾俊飞,潘俊辉,王鹏,黄婉仪,朱琳,喻清和,朱汉平,杨辉,叶振宇,邱志楠.中西医结合治疗肺炎喘嗽(痰热壅肺证)的多中心临床研究[J].中国实验方剂学杂志,2012,18(13):259-262.
作者姓名:曾俊飞  潘俊辉  王鹏  黄婉仪  朱琳  喻清和  朱汉平  杨辉  叶振宇  邱志楠
作者单位:广州医学院第一附属医院,广州,510120
基金项目:国家中医药管理局"十一五"重点肺病专科建设项目(19J1X1L407K222)
摘    要:目的:观察中西医结合方案治疗肺炎喘嗽(痰热壅肺证)的临床疗效.方法:采用多中心、单盲随机对照试验方法,将162例患者分为治疗组(101例)和对照组(61例).对照组予以头孢哌酮钠静脉滴注,每次2.0g,每日2次,并配合对症治疗;治疗组在对照组治疗基础上予以肺炎喘嗽分组痰热协作方基础方药加减治疗.两组疗程均为10d.结果:治疗组痊愈48例,显效40例,好转13例,痊愈率47.52%,愈显率87.13%;对照组痊愈18例,显效25例,好转17例,无效1例,痊愈率29.51%,愈显率70.49%,治疗组疗效明显优于对照组(P<0.05).结论:中西医结合治疗肺炎喘嗽(痰热壅肺证)的临床疗效显著.

关 键 词:肺炎喘嗽  痰热壅肺证  中西医结合  多中心临床研究
收稿时间:2012/2/15 0:00:00

Clinical Study on Combined Therapy of Traditional Chinese and Western Medicine for Pneumonia Cough by a Multicenter Clinical Trial
ZENG Jun-fei,PAN Jun-hui,WANG Peng,HUANG Wan-yi,ZHU Lin,YU Qing-he,ZHU Han-ping,YANG Hui,YE Zhen-yu and QIU Zhi-nan.Clinical Study on Combined Therapy of Traditional Chinese and Western Medicine for Pneumonia Cough by a Multicenter Clinical Trial[J].China Journal of Experimental Traditional Medical Formulae,2012,18(13):259-262.
Authors:ZENG Jun-fei  PAN Jun-hui  WANG Peng  HUANG Wan-yi  ZHU Lin  YU Qing-he  ZHU Han-ping  YANG Hui  YE Zhen-yu and QIU Zhi-nan
Institution:First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China;First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China
Abstract:Objective: To observe efficiency of combining traditional Chinese and western medicine treatment for pneumonia cough (syndrome of phlegm-heat obstructing lung). Method: Multi-center, single-blind randomized controlled trial method was used, and 162 cases were divided into the treatment group (n=101) and the control group (n=61). The control group was given cefoperazone sodium intravenous drip, every time 2.0 g, 2 twice a day, and cooperated with symptomatic treatment; and the treatment group was given traditional Chinese medicine treatment combined with the western medicine, 10 days being as one course. Result: in the treatment group 48 cases were cured, 40 cases were markedly improved, 13 cases was effective, recovery rate was 47.52%, the cure and marked effectiveness rate was 87.13%; In the control group 18 cases was cured, 25 cases were markedly improved, 17 cases showed effective, recovery rate was 29.51%, the cure and marked effectiveness rate was 70.49%.The clinical effect in the treatment group was superior to that in the control group(P<0.05). Conclusion: The treatment of combining traditional Chinese and western medicine for pneumonia cough (syndrome of phlegm-heat obstructing lung) is significant.
Keywords:pneumonia cough  syndrome of phlegm-heat obstructing lung  traditional Chinese and western medicine  Multi center clinical study
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