参脉注射液联合利血生治疗化疗后白细胞减少症

目的:观察参脉注射液联合利血生治疗化疗后白细胞减少症的临床疗效.方法:将符合病例入选标准的60例患者随机分为观察组、对照组各30例.两组均给予利血生片、维生素C、维生素B口服,观察组同时给予参麦注射液(每次20mL,1次/d,静脉滴注)治疗.两组疗程均为4周,治疗结束后观察临床疗效及白细胞变化情况.结果:显效率观察组36.67％,对照组20.00％,两组差异显著(P＜0.05)；总有效率观察组76.67％,对照组66.67％,两组差异显著(P＜0.05).两组白细胞计数情况治疗后1周均迅速降低,与治疗前比差异显著(P＜0.05)；治疗后2周两组白细胞计数继续下降,与治疗前比差异显著(P＜0.05)；治疗后3周均有所回升,但观察组(3.58±0.4) ×109/L]较对照组(2.82±0.6)×109L]改善更为显著(P＜0.05)；治疗后4周观察组为(4.58±0.B5) ×109/L,已接近正常,与对照组(3.20±0.74)×109/L]相比差异显著(P＜0.05).结论:利血生片联合参麦注射液治疗化疗后白细胞减少症临床疗效显著.

Combination of Shenmai Injection with Leucogen Tablets for Treatment of Leucopenia after Chemotherapy

Objective: To observe the clinical efficacy of the joint Shenmai injection with Leucogen tablets for leukopenia after chemotherapy. Method: Sixty patients were randomly divided into observation group and control group(n=30 each). Two groups were given Leucogen tablets, vitamin C tablets, vitamin B tablets in the treatment, while giving the observation group Shenmai injection. Two groups are treated for 4 weeks for a course, a clinical effect observed after treatment and changes in white blood cells. Result: The observation group was 36.67% significant efficiency, the control group was 20.00%, comparison showed significant difference (P<0.05); the total effective rate was 76.67% in the observation group, 66.67% in the control group(P<0.05). In both groups, the white blood cell count after the first week of treatment was rapidly reduced, compared with before treatment (P<0.05). Two weeks after treatment, white blood cell count in two groups continued to decline, with significant difference before treatment (P<0.05); 3 weeks after treatment had rebounded. The white blood cell count was(3.58±0.4)×10⁹/L in the observation group and (2.82±0.6)×10⁹/L in the controls after 3 weeks treatment (P<0.05);and (4.58±0.85)×10⁹/L and (3.20±0.74)×10⁹/L after 4 weeks treatment accordingly(P<0.05). Conclusion: Shenmai injection with Leucogen tablets for leukopenia after chemotherapy is effective.