川乌高温烘制工艺优选

目的:优选川乌高温烘制工艺.方法:HPLC和滴定法测定炮制品中6种生物碱和总生物碱的含量,并以此为指标,选取烘制时间、烘制温度及软化方式等为考察因素,采用正交试验法综合评价其高温烘制工艺.结果:川乌高温烘制的最佳工艺为A5B3C1,即川乌经润透法处理,110℃烘制8h.结论:该优选工艺简单可行且易于控制,可替代川乌传统炮制工艺.

Optimization of High Temperature Baking Technology of Aconitum carmichaeli

Objective: To optimize high temperature baking process of Aconitum carmichaeli.Method: With the content of six kinds of alkaloid and total alkaloids in processed products were determined by HPLC and titration method,and with them as indexes,taking baking time,baking temperature and softening method as factors,orthogonal test was used to comprehensive evaluate high temperature baking technology of A.carmichaeli.Result: Optimum high temperature baking technology of A.carmichaeli was A5B3C1,as that of A.carmichaeli was treatmented by moistening method,baked 8 h at 110 ℃.Conclusion: This optimized technology was simple,practical and easy to control,it could be instead of traditional processing technology of A.carmichaeli as a new method.